Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | ARG111 |
| C | HOH312 |
| A | CYS138 |
| A | ARG178 |
| A | HOH319 |
| A | HOH336 |
| A | HOH345 |
| A | HOH352 |
| C | ARG111 |
| C | ARG178 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 202 |
| Chain | Residue |
| A | ALA96 |
| A | ILE97 |
| A | LYS118 |
| B | THR198 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 203 |
| Chain | Residue |
| A | SER71 |
| A | HOH302 |
| A | HOH303 |
| A | HOH370 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue AES A 204 |
| Chain | Residue |
| A | GLY140 |
| A | ARG141 |
| A | GLY142 |
| A | ASP143 |
| A | SER144 |
| A | MET159 |
| A | GLY161 |
| A | VAL164 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 205 |
| Chain | Residue |
| A | ARG45 |
| A | GLY48 |
| A | GLN50 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 206 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue PGE A 207 |
| Chain | Residue |
| A | THR107 |
| A | ARG111 |
| A | ASN167 |
| A | ASN169 |
| A | CYS171 |
| A | GLY172 |
| A | HOH315 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| A | ARG130 |
| B | ARG130 |
| B | HOH302 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue AES B 202 |
| Chain | Residue |
| B | MET139 |
| B | GLY140 |
| B | ARG141 |
| B | GLY142 |
| B | ASP143 |
| B | SER144 |
| B | MET159 |
| B | GLY161 |
| B | GLY162 |
| B | HOH303 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 203 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 204 |
| Chain | Residue |
| B | GLY39 |
| B | VAL40 |
| B | ARG57 |
| B | HOH318 |
| B | HOH361 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 205 |
| Chain | Residue |
| B | ARG111 |
| B | ASN167 |
| B | ASN169 |
| B | CYS171 |
| D | TYR110 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 206 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 201 |
| site_id | AD6 |
| Number of Residues | 12 |
| Details | binding site for residue AES C 202 |
| Chain | Residue |
| C | TYR124 |
| C | MET139 |
| C | GLY140 |
| C | ARG141 |
| C | GLY142 |
| C | SER144 |
| C | MET159 |
| C | SER160 |
| C | GLY161 |
| C | GLY162 |
| C | HOH305 |
| C | HOH339 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 203 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 204 |
| Chain | Residue |
| C | ARG184 |
| C | PRO187 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue PEG C 205 |
| Chain | Residue |
| C | GLY39 |
| C | VAL40 |
| C | ARG57 |
| C | VAL58 |
| C | PHE59 |
| C | HOH317 |
| C | HOH327 |
| site_id | AE1 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 D 201 |
| Chain | Residue |
| B | ARG111 |
| B | CYS138 |
| B | ARG178 |
| B | HOH329 |
| D | ARG111 |
| D | CYS138 |
| D | ARG178 |
| D | HOH309 |
| D | HOH312 |
| D | HOH314 |
| D | HOH342 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 202 |
| Chain | Residue |
| B | HOH383 |
| D | ARG90 |
| B | ASN81 |
| site_id | AE3 |
| Number of Residues | 9 |
| Details | binding site for residue AES D 203 |
| Chain | Residue |
| D | MET139 |
| D | GLY140 |
| D | ARG141 |
| D | GLY142 |
| D | ASP143 |
| D | SER144 |
| D | MET159 |
| D | SER160 |
| D | GLY162 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL D 204 |
| Chain | Residue |
| D | ALA96 |
| D | ILE97 |
| D | LYS118 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
| Chain | Residue | Details |
| A | VAL32-CYS37 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSWF |
| Chain | Residue | Details |
| A | CYS138-PHE149 | |
