Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | ARG25 |
| A | GLY26 |
| A | ALA27 |
| A | THR28 |
| A | HOH302 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 202 |
| Chain | Residue |
| A | HOH461 |
| A | ALA96 |
| A | ILE97 |
| A | LYS118 |
| A | HOH347 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 203 |
| Chain | Residue |
| A | ARG184 |
| A | VAL185 |
| A | GLY186 |
| A | HOH367 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 204 |
| Chain | Residue |
| A | LYS29 |
| A | THR74 |
| A | LEU75 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 205 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 206 |
| Chain | Residue |
| A | ASN167 |
| A | HOH372 |
| A | HOH393 |
| D | SER83 |
| D | TYR110 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | ASN12 |
| B | ARG45 |
| B | HOH319 |
| B | HOH326 |
| C | GLN191 |
| C | TYR192 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 202 |
| Chain | Residue |
| B | ARG45 |
| B | GLY48 |
| B | GLN50 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 203 |
| Chain | Residue |
| B | ALA96 |
| B | ILE97 |
| B | LYS118 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 204 |
| Chain | Residue |
| B | ASN12 |
| B | HOH324 |
| C | ARG57 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 205 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 206 |
| Chain | Residue |
| B | GLU126 |
| B | SER160 |
| B | GLY161 |
| B | HOH388 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 207 |
| Chain | Residue |
| B | ARG57 |
| B | VAL58 |
| B | PHE59 |
| B | HOH304 |
| B | HOH308 |
| C | ILE43 |
| C | GLN50 |
| C | HOH307 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue TRS B 208 |
| Chain | Residue |
| B | ASN62 |
| B | ARG64 |
| B | PRO187 |
| B | HOH315 |
| B | HOH346 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 C 201 |
| Chain | Residue |
| B | ARG111 |
| B | ARG178 |
| B | HOH398 |
| C | ARG111 |
| C | ARG178 |
| C | HOH334 |
| C | HOH351 |
| C | HOH387 |
| C | HOH393 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 202 |
| Chain | Residue |
| C | ARG45 |
| C | GLN50 |
| C | HOH374 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue CL C 203 |
| Chain | Residue |
| C | ALA95 |
| C | ALA96 |
| C | HOH443 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 204 |
| Chain | Residue |
| C | ALA125 |
| C | HOH332 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 205 |
| Chain | Residue |
| A | GLY39 |
| A | VAL40 |
| A | ARG57 |
| B | ASN167 |
| C | ASN81 |
| C | SER83 |
| C | HOH304 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 206 |
| Chain | Residue |
| C | THR108 |
| C | ARG111 |
| C | HOH310 |
| C | HOH312 |
| C | HOH318 |
| D | ASN13 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 207 |
| Chain | Residue |
| C | HIS36 |
| C | PHE59 |
| C | TYR124 |
| C | GLU126 |
| C | SER160 |
| C | GLY161 |
| C | HOH332 |
| C | HOH368 |
| site_id | AE4 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 D 201 |
| Chain | Residue |
| D | ARG178 |
| D | HOH332 |
| D | HOH339 |
| D | HOH374 |
| D | HOH392 |
| A | ARG111 |
| A | CYS138 |
| A | ARG178 |
| A | HOH403 |
| D | ARG111 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue CL D 202 |
| Chain | Residue |
| D | TYR82 |
| D | GLY109 |
| D | TYR110 |
| D | NA204 |
| D | HOH388 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue CL D 203 |
| Chain | Residue |
| B | HOH314 |
| D | GLY39 |
| D | VAL40 |
| D | ARG57 |
| D | HOH438 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue NA D 204 |
| Chain | Residue |
| A | HOH393 |
| D | ASN81 |
| D | TYR82 |
| D | SER83 |
| D | CL202 |
| D | HOH329 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 205 |
| Chain | Residue |
| B | GLY84 |
| D | TYR124 |
| D | GLU126 |
| D | SER160 |
| D | GLY161 |
| D | HOH381 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
| Chain | Residue | Details |
| A | VAL32-CYS37 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSWF |
| Chain | Residue | Details |
| A | CYS138-PHE149 | |
