Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0050518 | molecular_function | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity |
| A | 0070567 | molecular_function | cytidylyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue Q9T A 401 |
| Chain | Residue |
| A | ARG157 |
| A | SER264 |
| A | VAL266 |
| A | GLU267 |
| A | HOH529 |
| A | GLN158 |
| A | VAL161 |
| A | ILE177 |
| A | ALA203 |
| A | GLN238 |
| A | VAL239 |
| A | LEU245 |
| A | PHE249 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue TRS A 402 |
| Chain | Residue |
| A | LYS195 |
| A | LYS195 |
| A | ASP196 |
| A | ALA199 |
| A | VAL200 |
| A | TYR274 |
| A | HOH532 |
| A | HOH532 |
| A | HOH577 |
| A | HOH577 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue ACT A 403 |
| Chain | Residue |
| A | PRO120 |
| A | GLU121 |
| A | GLU191 |
| A | LEU244 |
| A | HIS271 |
| A | CD407 |
| A | HOH505 |
| A | HOH535 |
| A | HOH571 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue K A 404 |
| Chain | Residue |
| A | LYS123 |
| A | GLU141 |
| A | ASP147 |
| A | HOH502 |
| A | HOH567 |
| A | HOH604 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue K A 405 |
| Chain | Residue |
| A | GLU141 |
| A | ASP169 |
| A | CD406 |
| A | HOH502 |
| A | HOH572 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CD A 406 |
| Chain | Residue |
| A | GLU138 |
| A | GLU141 |
| A | ASP169 |
| A | K405 |
| A | HOH534 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 407 |
| Chain | Residue |
| A | GLU121 |
| A | GLU191 |
| A | HIS271 |
| A | ACT403 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CD A 408 |
| Chain | Residue |
| A | GLU167 |
| A | HOH514 |
| A | HOH610 |
| A | HOH624 |
| A | HOH624 |
Functional Information from PROSITE/UniProt
| site_id | PS01295 |
| Number of Residues | 8 |
| Details | ISPD 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. VCIHDSAR |
| Chain | Residue | Details |
| A | VAL175-ARG182 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG91 | |
| A | LYS98 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Positions MEP for the nucleophilic attack => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG228 | |
| A | LYS284 | |
