Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5MQZ

Archaeal branched-chain amino acid aminotransferase from Archaeoglobus fulgidus; holoform

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004084	molecular_function	branched-chain-amino-acid transaminase activity
A	0008483	molecular_function	transaminase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009081	biological_process	branched-chain amino acid metabolic process
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009097	biological_process	isoleucine biosynthetic process
A	0009098	biological_process	L-leucine biosynthetic process
A	0009099	biological_process	valine biosynthetic process
A	0019752	biological_process	carboxylic acid metabolic process
A	0046394	biological_process	carboxylic acid biosynthetic process
A	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
A	0052654	molecular_function	L-leucine transaminase activity
A	0052655	molecular_function	L-valine transaminase activity
A	0052656	molecular_function	L-isoleucine transaminase activity
B	0003824	molecular_function	catalytic activity
B	0004084	molecular_function	branched-chain-amino-acid transaminase activity
B	0008483	molecular_function	transaminase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009081	biological_process	branched-chain amino acid metabolic process
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009097	biological_process	isoleucine biosynthetic process
B	0009098	biological_process	L-leucine biosynthetic process
B	0009099	biological_process	valine biosynthetic process
B	0019752	biological_process	carboxylic acid metabolic process
B	0046394	biological_process	carboxylic acid biosynthetic process
B	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
B	0052654	molecular_function	L-leucine transaminase activity
B	0052655	molecular_function	L-valine transaminase activity
B	0052656	molecular_function	L-isoleucine transaminase activity
C	0003824	molecular_function	catalytic activity
C	0004084	molecular_function	branched-chain-amino-acid transaminase activity
C	0008483	molecular_function	transaminase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009081	biological_process	branched-chain amino acid metabolic process
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009097	biological_process	isoleucine biosynthetic process
C	0009098	biological_process	L-leucine biosynthetic process
C	0009099	biological_process	valine biosynthetic process
C	0019752	biological_process	carboxylic acid metabolic process
C	0046394	biological_process	carboxylic acid biosynthetic process
C	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
C	0052654	molecular_function	L-leucine transaminase activity
C	0052655	molecular_function	L-valine transaminase activity
C	0052656	molecular_function	L-isoleucine transaminase activity
D	0003824	molecular_function	catalytic activity
D	0004084	molecular_function	branched-chain-amino-acid transaminase activity
D	0008483	molecular_function	transaminase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009081	biological_process	branched-chain amino acid metabolic process
D	0009082	biological_process	branched-chain amino acid biosynthetic process
D	0009097	biological_process	isoleucine biosynthetic process
D	0009098	biological_process	L-leucine biosynthetic process
D	0009099	biological_process	valine biosynthetic process
D	0019752	biological_process	carboxylic acid metabolic process
D	0046394	biological_process	carboxylic acid biosynthetic process
D	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
D	0052654	molecular_function	L-leucine transaminase activity
D	0052655	molecular_function	L-valine transaminase activity
D	0052656	molecular_function	L-isoleucine transaminase activity
E	0003824	molecular_function	catalytic activity
E	0004084	molecular_function	branched-chain-amino-acid transaminase activity
E	0008483	molecular_function	transaminase activity
E	0008652	biological_process	amino acid biosynthetic process
E	0009081	biological_process	branched-chain amino acid metabolic process
E	0009082	biological_process	branched-chain amino acid biosynthetic process
E	0009097	biological_process	isoleucine biosynthetic process
E	0009098	biological_process	L-leucine biosynthetic process
E	0009099	biological_process	valine biosynthetic process
E	0019752	biological_process	carboxylic acid metabolic process
E	0046394	biological_process	carboxylic acid biosynthetic process
E	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
E	0052654	molecular_function	L-leucine transaminase activity
E	0052655	molecular_function	L-valine transaminase activity
E	0052656	molecular_function	L-isoleucine transaminase activity
F	0003824	molecular_function	catalytic activity
F	0004084	molecular_function	branched-chain-amino-acid transaminase activity
F	0008483	molecular_function	transaminase activity
F	0008652	biological_process	amino acid biosynthetic process
F	0009081	biological_process	branched-chain amino acid metabolic process
F	0009082	biological_process	branched-chain amino acid biosynthetic process
F	0009097	biological_process	isoleucine biosynthetic process
F	0009098	biological_process	L-leucine biosynthetic process
F	0009099	biological_process	valine biosynthetic process
F	0019752	biological_process	carboxylic acid metabolic process
F	0046394	biological_process	carboxylic acid biosynthetic process
F	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
F	0052654	molecular_function	L-leucine transaminase activity
F	0052655	molecular_function	L-valine transaminase activity
F	0052656	molecular_function	L-isoleucine transaminase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CL A 301

Chain	Residue
A	SER141
A	HOH477
B	SER141
B	HOH467
B	HOH475

site_id	AC2
Number of Residues	2
Details	binding site for residue PEG A 302

Chain	Residue
A	ASN14
A	LYS116

site_id	AC3
Number of Residues	13
Details	binding site for residue TAM A 303

Chain	Residue
A	HOH409
A	HOH410
A	HOH438
A	HOH444
A	HOH452
C	THR228
C	ASN229
C	HOH408
F	THR228
F	ASN229
F	HOH329
A	THR228
A	ASN229

site_id	AC4
Number of Residues	1
Details	binding site for residue EDO B 301

Chain	Residue
B	LYS116

site_id	AC5
Number of Residues	3
Details	binding site for residue EDO B 302

Chain	Residue
B	ILE63
B	ILE65
F	GLU290

site_id	AC6
Number of Residues	10
Details	binding site for residue TAM B 303

Chain	Residue
B	THR228
B	ASN229
B	HOH411
B	HOH418
B	HOH447
B	HOH493
D	THR228
D	ASN229
E	THR228
E	ASN229

site_id	AC7
Number of Residues	5
Details	binding site for residue CL C 301

Chain	Residue
C	SER141
C	HOH467
D	SER141
D	HOH428
D	HOH472

site_id	AC8
Number of Residues	5
Details	binding site for residue PEG D 301

Chain	Residue
D	TYR5
D	GLY8
D	GLU72
D	ILE73
D	GLU76

site_id	AC9
Number of Residues	3
Details	binding site for residue EDO D 302

Chain	Residue
C	TYR27
D	LLP150
D	GLY186

site_id	AD1
Number of Residues	5
Details	binding site for residue CL E 301

Chain	Residue
E	SER141
E	HOH444
E	HOH484
F	SER141
F	HOH365

Functional Information from PROSITE/UniProt

site_id	PS00770
Number of Residues	29
Details	AA_TRANSFER_CLASS_4 Aminotransferases class-IV signature. EgSgdNIFvvknga......ItTpptinn..LrGItR

Chain	Residue	Details
A	GLU183-ARG211

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255

Chain	Residue	Details
A	LLP150
B	LLP150
C	LLP150
D	LLP150
E	LLP150
F	LLP150

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)