5MMD

TMB-1. Structural insights into TMB-1 and the role of residue 119 and 228 in substrate and inhibitor binding

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0008800	molecular_function	beta-lactamase activity
E	0016787	molecular_function	hydrolase activity
E	0017001	biological_process	antibiotic catabolic process
E	0042597	cellular_component	periplasmic space
E	0046677	biological_process	response to antibiotic
E	0046872	molecular_function	metal ion binding
F	0008800	molecular_function	beta-lactamase activity
F	0016787	molecular_function	hydrolase activity
F	0017001	biological_process	antibiotic catabolic process
F	0042597	cellular_component	periplasmic space
F	0046677	biological_process	response to antibiotic
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN E 401

Chain	Residue
E	ASP120
E	CYS221
E	HIS263
E	ZN403
E	HOH649

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site_id	AC2
Number of Residues	5
Details	binding site for residue ZN E 402

Chain	Residue
E	HOH728
E	HIS285
E	HOH560
E	HOH702
E	HOH724

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site_id	AC3
Number of Residues	5
Details	binding site for residue ZN E 403

Chain	Residue
E	HIS116
E	HIS118
E	HIS196
E	ZN401
E	HOH649

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site_id	AC4
Number of Residues	1
Details	binding site for residue CL E 404

Chain	Residue
E	HOH547

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site_id	AC5
Number of Residues	3
Details	binding site for residue CL E 405

Chain	Residue
E	GLU255
E	HOH613
E	HOH697

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site_id	AC6
Number of Residues	5
Details	binding site for residue ZN F 401

Chain	Residue
F	ASP120
F	CYS221
F	HIS263
F	ZN402
F	HOH510

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site_id	AC7
Number of Residues	7
Details	binding site for residue ZN F 402

Chain	Residue
F	HIS116
F	HIS118
F	HIS196
F	THR197
F	ZN401
F	HOH510
F	HOH595

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