5MLR

Plantago Major multifunctional oxidoreductase V150M mutant in complex with citral and NADP+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003854	molecular_function	3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity
A	0006629	biological_process	lipid metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CL A 401

Chain	Residue
A	GLY145
A	ARG146
A	LYS147
A	TYR179
A	NAP406

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site_id	AC2
Number of Residues	4
Details	binding site for residue NA A 402

Chain	Residue
A	ASP252
A	ARG369
A	HOH772
A	HOH886

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site_id	AC3
Number of Residues	3
Details	binding site for residue NA A 403

Chain	Residue
A	PHE282
A	LYS283
A	HIS286

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site_id	AC4
Number of Residues	14
Details	binding site for residue GRQ A 404

Chain	Residue
A	LYS147
A	PHE153
A	ILE156
A	ASN205
A	MET215
A	PHE343
A	ALA346
A	VAL347
A	ASP349
A	ILE350
A	GRQ405
A	HOH526
A	HOH934
A	HOH965

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site_id	AC5
Number of Residues	14
Details	binding site for residue GRQ A 405

Chain	Residue
A	LYS147
A	MET150
A	PHE153
A	ASN205
A	MET215
A	PHE343
A	ALA346
A	VAL347
A	ILE350
A	CYS352
A	GRQ404
A	HOH520
A	HOH526
A	HOH940

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site_id	AC6
Number of Residues	35
Details	binding site for residue NAP A 406

Chain	Residue
A	GLY33
A	VAL34
A	THR35
A	GLY36
A	ILE37
A	ALA62
A	ARG63
A	ARG64
A	CYS80
A	ASP81
A	ILE82
A	VAL104
A	THR105
A	TRP106
A	GLN143
A	THR144
A	TYR179
A	PRO203
A	GLY204
A	ILE206
A	SER213
A	MET214
A	MET215
A	CL401
A	HOH527
A	HOH562
A	HOH571
A	HOH592
A	HOH607
A	HOH637
A	HOH643
A	HOH660
A	HOH679
A	HOH766
A	HOH790

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