5MKY
BROMODOMAIN OF HUMAN BRD9 WITH 4-chloro-2-methyl-5-((2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)amino)pyridazin-3(2H)-one
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue I0D A 201 |
| Chain | Residue |
| A | PHE44 |
| A | HOH315 |
| A | HOH322 |
| A | HOH335 |
| A | HOH387 |
| A | PHE45 |
| A | PRO48 |
| A | VAL49 |
| A | ILE53 |
| A | ALA54 |
| A | TYR99 |
| A | ASN100 |
| A | TYR106 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue I0D A 202 |
| Chain | Residue |
| A | LEU28 |
| A | HIS31 |
| A | PRO55 |
| A | GLY56 |
| A | ILE60 |
| A | TYR99 |
| A | MET121 |
| A | SER122 |
| A | HOH407 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding => ECO:0000269|PubMed:26365797 |
| Chain | Residue | Details |
| A | ILE53 | |
| A | TYR106 |
