5MIK

X-ray structure of carboplatin-encapsulated horse spleen apoferritin (rotating anode data)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005737	cellular_component	cytoplasm
A	0005776	cellular_component	autophagosome
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0031410	cellular_component	cytoplasmic vesicle
A	0044754	cellular_component	autolysosome
A	0046872	molecular_function	metal ion binding
A	0070288	cellular_component	ferritin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CD A 201

Chain	Residue
A	GLU11
A	HOH360
A	HOH416

---

site_id	AC2
Number of Residues	3
Details	binding site for residue CD A 202

Chain	Residue
A	GLU53
A	GLU56
A	HOH310

---

site_id	AC3
Number of Residues	4
Details	binding site for residue CD A 203

Chain	Residue
A	CL214
A	GLU56
A	GLU57
A	GLU60

---

site_id	AC4
Number of Residues	2
Details	binding site for residue CD A 204

Chain	Residue
A	ASP80
A	CL213

---

site_id	AC5
Number of Residues	1
Details	binding site for residue CD A 205

Chain	Residue
A	GLU88

---

site_id	AC6
Number of Residues	6
Details	binding site for residue CD A 206

Chain	Residue
A	GLU130
A	GLU130
A	GLU130
A	CL212
A	CL212
A	CL212

---

site_id	AC7
Number of Residues	2
Details	binding site for residue CD A 207

Chain	Residue
A	HIS114
A	CYS126

---

site_id	AC8
Number of Residues	4
Details	binding site for residue CD A 208

Chain	Residue
A	CYS48
A	HIS49
A	ARG52
A	HOH468

---

site_id	AC9
Number of Residues	2
Details	binding site for residue CD A 209

Chain	Residue
A	GLU45
A	CD211

---

site_id	AD1
Number of Residues	3
Details	binding site for residue CD A 210

Chain	Residue
A	ASP127
A	ASP127
A	ASP127

---

site_id	AD2
Number of Residues	3
Details	binding site for residue CD A 211

Chain	Residue
A	GLU45
A	CD209
A	PT218

---

site_id	AD3
Number of Residues	5
Details	binding site for residue CL A 212

Chain	Residue
A	GLU130
A	GLU130
A	CD206
A	CD206
A	CD206

---

site_id	AD4
Number of Residues	1
Details	binding site for residue CL A 213

Chain	Residue
A	CD204

---

site_id	AD5
Number of Residues	3
Details	binding site for residue CL A 214

Chain	Residue
A	GLU57
A	GLU60
A	CD203

---

site_id	AD6
Number of Residues	6
Details	binding site for residue SO4 A 215

Chain	Residue
A	GLN6
A	ASN7
A	HOH305
A	HOH307
A	HOH348
A	HOH417

---

site_id	AD7
Number of Residues	5
Details	binding site for residue GOL A 216

Chain	Residue
A	GLN3
A	ILE100
A	VAL101
A	LYS104
A	HOH429

---

site_id	AD8
Number of Residues	5
Details	binding site for residue GOL A 217

Chain	Residue
A	TYR36
A	ASP41
A	GLU163
A	HOH334
A	HOH385

---

site_id	AD9
Number of Residues	4
Details	binding site for residue PT A 218

Chain	Residue
A	GLU45
A	HIS49
A	GLU53
A	CD211

---

site_id	AE1
Number of Residues	2
Details	binding site for residue PT A 219

Chain	Residue
A	HIS132
A	ASP135

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEshFLdeevklIK

Chain	Residue	Details
A	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EkREgaERLLkmQNqRgGR

Chain	Residue	Details
A	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Region: {"description":"Catalytic site for iron oxidation"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"7026284","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---