5MIJ

X-ray structure of carboplatin-encapsulated horse spleen apoferritin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005737	cellular_component	cytoplasm
A	0005764	cellular_component	lysosome
A	0005776	cellular_component	autophagosome
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0031410	cellular_component	cytoplasmic vesicle
A	0044754	cellular_component	autolysosome
A	0046872	molecular_function	metal ion binding
A	0070288	cellular_component	ferritin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue CD A 201

Chain	Residue
A	GLU11
A	CL213
A	HOH311
A	HOH384

---

site_id	AC2
Number of Residues	3
Details	binding site for residue CD A 202

Chain	Residue
A	GLU53
A	GLU56
A	HOH315

---

site_id	AC3
Number of Residues	4
Details	binding site for residue CD A 203

Chain	Residue
A	GLU60
A	CL218
A	GLU56
A	GLU57

---

site_id	AC4
Number of Residues	2
Details	binding site for residue CD A 204

Chain	Residue
A	ASP80
A	CL212

---

site_id	AC5
Number of Residues	4
Details	binding site for residue CD A 205

Chain	Residue
A	GLU88
A	HOH307
A	HOH420
A	HOH428

---

site_id	AC6
Number of Residues	6
Details	binding site for residue CD A 206

Chain	Residue
A	GLU130
A	GLU130
A	GLU130
A	CL211
A	CL211
A	CL211

---

site_id	AC7
Number of Residues	4
Details	binding site for residue CD A 207

Chain	Residue
A	HIS114
A	CYS126
A	GLU130
A	HOH531

---

site_id	AC8
Number of Residues	4
Details	binding site for residue CD A 208

Chain	Residue
A	CYS48
A	HIS49
A	ARG52
A	HOH533

---

site_id	AC9
Number of Residues	3
Details	binding site for residue CD A 209

Chain	Residue
A	GLU45
A	CD210
A	HOH481

---

site_id	AD1
Number of Residues	2
Details	binding site for residue CD A 210

Chain	Residue
A	GLU45
A	CD209

---

site_id	AD2
Number of Residues	5
Details	binding site for residue CL A 211

Chain	Residue
A	GLU130
A	GLU130
A	CD206
A	CD206
A	CD206

---

site_id	AD3
Number of Residues	2
Details	binding site for residue CL A 212

Chain	Residue
A	ASP80
A	CD204

---

site_id	AD4
Number of Residues	6
Details	binding site for residue CL A 213

Chain	Residue
A	SER9
A	THR10
A	GLU11
A	CD201
A	HOH479
A	HOH540

---

site_id	AD5
Number of Residues	1
Details	binding site for residue CD A 214

Chain	Residue
A	ASP127

---

site_id	AD6
Number of Residues	7
Details	binding site for residue SO4 A 215

Chain	Residue
A	GLN6
A	ASN7
A	HOH304
A	HOH313
A	HOH323
A	HOH408
A	HOH439

---

site_id	AD7
Number of Residues	1
Details	binding site for residue PT A 216

Chain	Residue
A	HIS132

---

site_id	AD8
Number of Residues	3
Details	binding site for residue PT A 217

Chain	Residue
A	GLU45
A	HIS49
A	GLU53

---

site_id	AD9
Number of Residues	3
Details	binding site for residue CL A 218

Chain	Residue
A	GLU57
A	GLU60
A	CD203

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEshFLdeevklIK

Chain	Residue	Details
A	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EkREgaERLLkmQNqRgGR

Chain	Residue	Details
A	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00085

Chain	Residue	Details
A	GLU53
A	GLU56
A	GLU57
A	GLU60
A	GLU63

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylserine => ECO:0000269|PubMed:7026284

Chain	Residue	Details
A	SER1

---