Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
| A | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 38 |
| Details | binding site for residue FAD A 401 |
| Chain | Residue |
| A | GLY12 |
| A | THR46 |
| A | ASN51 |
| A | GLY81 |
| A | PHE82 |
| A | VAL83 |
| A | ALA110 |
| A | THR111 |
| A | GLY112 |
| A | GLU159 |
| A | VAL243 |
| A | GLY14 |
| A | PHE246 |
| A | GLY276 |
| A | ASP277 |
| A | ARG284 |
| A | GLN285 |
| A | ILE286 |
| A | NAP402 |
| A | HOH505 |
| A | HOH511 |
| A | HOH519 |
| A | PRO15 |
| A | HOH526 |
| A | HOH529 |
| A | HOH539 |
| A | HOH544 |
| A | HOH555 |
| A | HOH561 |
| A | HOH563 |
| A | HOH591 |
| A | HOH639 |
| A | ALA16 |
| A | GLU35 |
| A | ARG36 |
| A | GLY41 |
| A | GLN42 |
| A | ASN45 |
| site_id | AC2 |
| Number of Residues | 29 |
| Details | binding site for residue NAP A 402 |
| Chain | Residue |
| A | ASN51 |
| A | ILE150 |
| A | GLY151 |
| A | GLY152 |
| A | GLY153 |
| A | ASP154 |
| A | SER155 |
| A | GLU158 |
| A | HIS174 |
| A | ARG175 |
| A | ARG176 |
| A | ARG180 |
| A | VAL202 |
| A | TYR237 |
| A | VAL238 |
| A | GLY239 |
| A | LEU240 |
| A | ARG284 |
| A | GLN285 |
| A | FAD401 |
| A | HOH505 |
| A | HOH523 |
| A | HOH524 |
| A | HOH534 |
| A | HOH542 |
| A | HOH545 |
| A | HOH550 |
| A | HOH556 |
| A | HOH575 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 403 |
| Chain | Residue |
| A | SER13 |
| A | GLU35 |
| A | GLY37 |
| A | ASN78 |
| A | HOH503 |
| A | HOH537 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | LYS5 |
| A | PRO121 |
| A | GLY122 |
| A | GLU123 |
| A | GLU124 |
| A | GLU125 |
| A | HOH525 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | ARG116 |
| A | ARG175 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 21 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CavCDGaf..FrnqeIlVIGGGD |
| Chain | Residue | Details |
| A | CYS134-ASP154 | |
