5M9N

Crystal structure of human TDRD1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue EDO A 701

Chain	Residue
A	SER537
A	ASP538
A	PHE539
A	LEU586
A	MET587

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site_id	AC2
Number of Residues	1
Details	binding site for residue EDO A 702

Chain	Residue
A	TYR575

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site_id	AC3
Number of Residues	6
Details	binding site for residue 2MR B 701

Chain	Residue
B	TYR575
B	TYR578
B	ASN580
B	HIS501
B	PHE551
B	TYR558

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site_id	AC4
Number of Residues	2
Details	binding site for residue EDO B 702

Chain	Residue
B	GLY574
B	TYR575

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site_id	AC5
Number of Residues	7
Details	binding site for Di-peptide GLY C 7 and 2MR C 8

Chain	Residue
A	HIS501
A	PHE551
A	TYR558
A	TYR575
A	TYR578
A	ASN580
C	GLY9

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site_id	AC6
Number of Residues	9
Details	binding site for Di-peptide 2MR C 8 and GLY C 9

Chain	Residue
A	HIS501
A	PHE551
A	ASP554
A	TYR558
A	TYR575
A	TYR578
A	ASN580
C	GLY7
C	2MR10

---

site_id	AC7
Number of Residues	5
Details	binding site for Di-peptide GLY C 9 and 2MR C 10

Chain	Residue
A	GLU553
A	ASP554
A	GLN556
A	TYR558
C	2MR8

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	118
Details	Domain: {"description":"Tudor 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00211","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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