5M9B

Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006811	biological_process	monoatomic ion transport
A	0006826	biological_process	iron ion transport
A	0009279	cellular_component	cell outer membrane
A	0015343	molecular_function	siderophore-iron transmembrane transporter activity
A	0015344	molecular_function	siderophore uptake transmembrane transporter activity
A	0015891	biological_process	siderophore transport
A	0019867	cellular_component	outer membrane
A	0033214	biological_process	siderophore-iron import into cell
A	0038023	molecular_function	signaling receptor activity
A	0042912	molecular_function	colicin transmembrane transporter activity
A	0042930	biological_process	enterobactin transport
A	0042931	molecular_function	enterobactin transmembrane transporter activity
A	0043213	biological_process	bacteriocin transport
A	0044718	biological_process	siderophore transmembrane transport
A	1903981	molecular_function	enterobactin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue ACY A 801

Chain	Residue
A	ARG41
A	THR629
A	TYR631
A	ILE659
A	HOH1020
A	HOH1025

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ACY A 802

Chain	Residue
A	TYR307
A	ASP89
A	ARG296
A	LEU305

---

site_id	AC3
Number of Residues	5
Details	binding site for residue ACY A 803

Chain	Residue
A	SER402
A	SER403
A	ILE434
A	ASN472
A	HOH998

---

site_id	AC4
Number of Residues	7
Details	binding site for residue ACY A 804

Chain	Residue
A	LYS40
A	ARG41
A	LEU662
A	VAL678
A	ASP679
A	TYR714
A	HOH982

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ACY A 805

Chain	Residue
A	THR665
A	SER673
A	SER716
A	THR718

---

site_id	AC6
Number of Residues	3
Details	binding site for residue ACY A 806

Chain	Residue
A	SER584
A	ASN586
A	MET613

---

site_id	AC7
Number of Residues	7
Details	binding site for residue EDO A 807

Chain	Residue
A	LEU374
A	ASN380
A	SER400
A	SER401
A	SER402
A	LEU468
A	ASN472

---

site_id	AC8
Number of Residues	7
Details	binding site for residue EDO A 808

Chain	Residue
A	ARG100
A	GLY102
A	TRP103
A	GLU106
A	GLN267
A	LEU322
A	GLU327

---

site_id	AC9
Number of Residues	10
Details	binding site for residue EDO A 809

Chain	Residue
A	ARG52
A	LEU59
A	ARG72
A	TYR631
A	GLN634
A	TYR657
A	TYR706
A	GLU708
A	HOH1027
A	HOH1061

---

site_id	AD1
Number of Residues	4
Details	binding site for residue EDO A 810

Chain	Residue
A	TYR485
A	GLU534
A	SER535
A	HOH907

---

site_id	AD2
Number of Residues	6
Details	binding site for residue EDO A 811

Chain	Residue
A	PRO28
A	ARG128
A	THR523
A	GLU570
A	GLY571
A	THR572

---

Functional Information from PROSITE/UniProt

site_id	PS01156
Number of Residues	18
Details	TONB_DEPENDENT_REC_2 TonB-dependent receptor (TBDR) proteins signature 2. AtynEpGRtFyTSLtAsF

Chain	Residue	Details
A	ALA704-PHE721

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	127
Details	Domain: {"description":"TBDR plug","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	567
Details	Domain: {"description":"TBDR beta-barrel","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	66
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	17
Details	Motif: {"description":"TonB C-terminal box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	23
Details	Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---