Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 601 |
| Chain | Residue |
| A | GLY401 |
| A | ASP406 |
| A | CYS408 |
| A | ASP411 |
| A | ASP412 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 602 |
| Chain | Residue |
| A | ASP50 |
| A | HOH867 |
| A | ASP42 |
| A | ASP44 |
| A | ASP46 |
| A | VAL48 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 603 |
| Chain | Residue |
| A | ASN122 |
| A | ASP183 |
| A | HIS217 |
| A | ILE218 |
| A | HOH701 |
| A | HOH729 |
| A | HOH778 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 604 |
| Chain | Residue |
| A | LYS216 |
| A | HIS217 |
| A | TYR219 |
| A | ASP225 |
| A | GLY226 |
| A | HOH787 |
| A | HOH826 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue K A 605 |
| Chain | Residue |
| A | TYR83 |
| A | ASP213 |
| A | EDO611 |
| A | HOH929 |
| A | HOH943 |
| A | HOH977 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 606 |
| Chain | Residue |
| A | ASP411 |
| A | ASP412 |
| A | ASP415 |
| A | PHE417 |
| A | HOH732 |
| A | HOH761 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 607 |
| Chain | Residue |
| A | TRP361 |
| A | HIS362 |
| A | GLY363 |
| A | HOH711 |
| B | TRP361 |
| B | EDO607 |
| B | HOH713 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 608 |
| Chain | Residue |
| A | THR259 |
| A | ASN291 |
| A | HOH727 |
| A | HOH961 |
| A | HOH1001 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 609 |
| Chain | Residue |
| A | GLU423 |
| A | ASN424 |
| A | ARG434 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 610 |
| Chain | Residue |
| A | TYR143 |
| A | TYR146 |
| A | HOH829 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 611 |
| Chain | Residue |
| A | TYR83 |
| A | HIS123 |
| A | PHE177 |
| A | ASP213 |
| A | K605 |
| A | HOH977 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 612 |
| Chain | Residue |
| A | ILE148 |
| A | TYR219 |
| A | GLY220 |
| A | TRP221 |
| A | HOH701 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue TRS A 613 |
| Chain | Residue |
| A | GLU421 |
| A | ASP425 |
| A | HOH752 |
| A | HOH822 |
| A | HOH878 |
| B | ALA378 |
| B | HOH755 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 601 |
| Chain | Residue |
| B | GLY401 |
| B | ASP406 |
| B | CYS408 |
| B | ASP411 |
| B | ASP412 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 602 |
| Chain | Residue |
| B | ASP42 |
| B | ASP44 |
| B | ASP46 |
| B | VAL48 |
| B | ASP50 |
| B | HOH809 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue NA B 603 |
| Chain | Residue |
| B | ASN122 |
| B | ASP183 |
| B | HIS217 |
| B | ILE218 |
| B | HOH710 |
| B | HOH712 |
| B | HOH757 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 604 |
| Chain | Residue |
| B | LYS216 |
| B | HIS217 |
| B | TYR219 |
| B | ASP225 |
| B | HOH877 |
| B | HOH879 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue K B 605 |
| Chain | Residue |
| B | EDO616 |
| B | HOH820 |
| B | HOH1018 |
| B | HOH1037 |
| B | TYR83 |
| B | ASP213 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 606 |
| Chain | Residue |
| B | ASP411 |
| B | ASP412 |
| B | ASP415 |
| B | PHE417 |
| B | HOH726 |
| B | HOH774 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 607 |
| Chain | Residue |
| A | EDO607 |
| A | HOH711 |
| A | HOH715 |
| B | HIS362 |
| B | GLY363 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 608 |
| Chain | Residue |
| A | ASN424 |
| B | ASP415 |
| B | GLY416 |
| B | HOH753 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 609 |
| Chain | Residue |
| B | LYS57 |
| B | TRP376 |
| B | VAL419 |
| B | GLU423 |
| B | EDO611 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 610 |
| Chain | Residue |
| B | ILE148 |
| B | TYR219 |
| B | GLY220 |
| B | TRP221 |
| B | HOH710 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 611 |
| Chain | Residue |
| B | ASP59 |
| B | TYR60 |
| B | LYS63 |
| B | GLU423 |
| B | ARG434 |
| B | EDO609 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 612 |
| Chain | Residue |
| B | GLU110 |
| B | HOH714 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 613 |
| Chain | Residue |
| B | THR259 |
| B | ASN291 |
| B | HOH893 |
| B | HOH910 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 614 |
| Chain | Residue |
| B | SER263 |
| B | TYR265 |
| B | GLU295 |
| B | HOH857 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 615 |
| Chain | Residue |
| B | VAL107 |
| B | GLU110 |
| B | ASN111 |
| B | HOH756 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 616 |
| Chain | Residue |
| B | TYR83 |
| B | HIS123 |
| B | ASP213 |
| B | K605 |
| B | HOH1037 |
