5M98

Crystal structure of urate oxidase from zebrafish

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004846	molecular_function	urate oxidase activity
A	0005777	cellular_component	peroxisome
A	0006144	biological_process	purine nucleobase metabolic process
A	0006145	biological_process	purine nucleobase catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0019628	biological_process	urate catabolic process
A	0046415	biological_process	urate metabolic process
A	0051289	biological_process	protein homotetramerization
B	0004846	molecular_function	urate oxidase activity
B	0005777	cellular_component	peroxisome
B	0006144	biological_process	purine nucleobase metabolic process
B	0006145	biological_process	purine nucleobase catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0019628	biological_process	urate catabolic process
B	0046415	biological_process	urate metabolic process
B	0051289	biological_process	protein homotetramerization
C	0004846	molecular_function	urate oxidase activity
C	0005777	cellular_component	peroxisome
C	0006144	biological_process	purine nucleobase metabolic process
C	0006145	biological_process	purine nucleobase catabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0019628	biological_process	urate catabolic process
C	0046415	biological_process	urate metabolic process
C	0051289	biological_process	protein homotetramerization
D	0004846	molecular_function	urate oxidase activity
D	0005777	cellular_component	peroxisome
D	0006144	biological_process	purine nucleobase metabolic process
D	0006145	biological_process	purine nucleobase catabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0019628	biological_process	urate catabolic process
D	0046415	biological_process	urate metabolic process
D	0051289	biological_process	protein homotetramerization
E	0004846	molecular_function	urate oxidase activity
E	0005777	cellular_component	peroxisome
E	0006144	biological_process	purine nucleobase metabolic process
E	0006145	biological_process	purine nucleobase catabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0019628	biological_process	urate catabolic process
E	0046415	biological_process	urate metabolic process
E	0051289	biological_process	protein homotetramerization
F	0004846	molecular_function	urate oxidase activity
F	0005777	cellular_component	peroxisome
F	0006144	biological_process	purine nucleobase metabolic process
F	0006145	biological_process	purine nucleobase catabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0019628	biological_process	urate catabolic process
F	0046415	biological_process	urate metabolic process
F	0051289	biological_process	protein homotetramerization
G	0004846	molecular_function	urate oxidase activity
G	0005777	cellular_component	peroxisome
G	0006144	biological_process	purine nucleobase metabolic process
G	0006145	biological_process	purine nucleobase catabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0019628	biological_process	urate catabolic process
G	0046415	biological_process	urate metabolic process
G	0051289	biological_process	protein homotetramerization
H	0004846	molecular_function	urate oxidase activity
H	0005777	cellular_component	peroxisome
H	0006144	biological_process	purine nucleobase metabolic process
H	0006145	biological_process	purine nucleobase catabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0019628	biological_process	urate catabolic process
H	0046415	biological_process	urate metabolic process
H	0051289	biological_process	protein homotetramerization

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	ACT_SITE: Charge relay system => ECO:0000250|UniProtKB:D0VWQ1

Chain	Residue	Details
A	LYS18
D	LYS18
D	THR63
D	HIS258
E	LYS18
E	THR63
E	HIS258
F	LYS18
F	THR63
F	HIS258
G	LYS18
A	THR63
G	THR63
G	HIS258
H	LYS18
H	THR63
H	HIS258
A	HIS258
B	LYS18
B	THR63
B	HIS258
C	LYS18
C	THR63
C	HIS258

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site_id	SWS_FT_FI2
Number of Residues	56
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q00511

Chain	Residue	Details
A	THR63
B	PHE165
B	ARG182
B	VAL229
B	GLN230
B	ASN256
C	THR63
C	ASP64
C	PHE165
C	ARG182
C	VAL229
A	ASP64
C	GLN230
C	ASN256
D	THR63
D	ASP64
D	PHE165
D	ARG182
D	VAL229
D	GLN230
D	ASN256
E	THR63
A	PHE165
E	ASP64
E	PHE165
E	ARG182
E	VAL229
E	GLN230
E	ASN256
F	THR63
F	ASP64
F	PHE165
F	ARG182
A	ARG182
F	VAL229
F	GLN230
F	ASN256
G	THR63
G	ASP64
G	PHE165
G	ARG182
G	VAL229
G	GLN230
G	ASN256
A	VAL229
H	THR63
H	ASP64
H	PHE165
H	ARG182
H	VAL229
H	GLN230
H	ASN256
A	GLN230
A	ASN256
B	THR63
B	ASP64

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