5M8H
ATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | histidine biosynthetic process |
| A | 0004821 | molecular_function | histidine-tRNA ligase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0000105 | biological_process | histidine biosynthetic process |
| B | 0004821 | molecular_function | histidine-tRNA ligase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0000105 | biological_process | histidine biosynthetic process |
| C | 0004821 | molecular_function | histidine-tRNA ligase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0000105 | biological_process | histidine biosynthetic process |
| D | 0004821 | molecular_function | histidine-tRNA ligase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| E | 0000105 | biological_process | histidine biosynthetic process |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0003879 | molecular_function | ATP phosphoribosyltransferase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008652 | biological_process | amino acid biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016757 | molecular_function | glycosyltransferase activity |
| F | 0000105 | biological_process | histidine biosynthetic process |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0003879 | molecular_function | ATP phosphoribosyltransferase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0008652 | biological_process | amino acid biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016757 | molecular_function | glycosyltransferase activity |
| G | 0000105 | biological_process | histidine biosynthetic process |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0003879 | molecular_function | ATP phosphoribosyltransferase activity |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0008652 | biological_process | amino acid biosynthetic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016757 | molecular_function | glycosyltransferase activity |
| H | 0000105 | biological_process | histidine biosynthetic process |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0003879 | molecular_function | ATP phosphoribosyltransferase activity |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0008652 | biological_process | amino acid biosynthetic process |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SR A 401 |
| Chain | Residue |
| A | ASP76 |
| A | THR78 |
| A | HOH585 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue SR A 402 |
| Chain | Residue |
| A | ASN144 |
| A | ASP147 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | LEU10 |
| A | ASP13 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | ASP379 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MPD A 405 |
| Chain | Residue |
| A | GLU237 |
| A | ARG287 |
| A | GLN303 |
| A | HOH568 |
| A | GLU127 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue MPD A 406 |
| Chain | Residue |
| A | ASP132 |
| A | LEU135 |
| A | ILE136 |
| A | PHE271 |
| A | GLY286 |
| A | THR305 |
| A | GLY306 |
| A | PHE307 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue MPD A 407 |
| Chain | Residue |
| A | GLN118 |
| A | LEU282 |
| A | ARG284 |
| A | SER308 |
| A | ASP310 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue SR B 401 |
| Chain | Residue |
| B | ASN144 |
| B | ASP147 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SR B 402 |
| Chain | Residue |
| B | ASP76 |
| B | THR78 |
| B | HOH558 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 403 |
| Chain | Residue |
| B | GLY109 |
| B | LEU110 |
| B | GLN280 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 404 |
| Chain | Residue |
| B | GLN381 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 405 |
| Chain | Residue |
| B | GLY125 |
| B | GLN303 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue MPD B 406 |
| Chain | Residue |
| B | GLN118 |
| B | LEU282 |
| B | ARG284 |
| B | SER308 |
| B | MET309 |
| B | ASP310 |
| B | HOH648 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue MPD B 407 |
| Chain | Residue |
| B | GLU259 |
| B | SER261 |
| B | TYR274 |
| B | ARG284 |
| B | HOH594 |
| F | GLN206 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue MPD B 408 |
| Chain | Residue |
| B | LEU20 |
| B | ASP147 |
| B | GLN319 |
| B | LEU320 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue SR C 401 |
| Chain | Residue |
| C | GLN381 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SR C 402 |
| Chain | Residue |
| C | ASN144 |
| C | ASP147 |
| C | HOH585 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue SR C 403 |
| Chain | Residue |
| C | ASP76 |
| C | THR78 |
| C | HOH587 |
| C | HOH617 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 404 |
| Chain | Residue |
| C | ARG383 |
| C | LEU384 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue MPD C 405 |
| Chain | Residue |
| C | GLU259 |
| C | SER261 |
| C | ARG284 |
| H | TYR105 |
| H | GLN206 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue MPD C 406 |
| Chain | Residue |
| C | PRO116 |
| C | GLN118 |
| C | LEU282 |
| C | SER308 |
| C | MET309 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue SR D 401 |
| Chain | Residue |
| D | GLN193 |
| D | GLN196 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue SR D 402 |
| Chain | Residue |
| D | ASP76 |
| D | THR78 |
| D | SER308 |
| D | HOH530 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue SR D 403 |
| Chain | Residue |
| D | ASN144 |
| D | ASP147 |
| site_id | AE7 |
| Number of Residues | 1 |
| Details | binding site for residue CL D 404 |
| Chain | Residue |
| D | LEU152 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue MPD D 405 |
| Chain | Residue |
| D | VAL102 |
| D | PRO116 |
| D | GLN118 |
| D | LEU282 |
| D | SER308 |
| D | ASP310 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue MPD D 406 |
| Chain | Residue |
| D | GLN354 |
| D | TYR356 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue CL E 301 |
| Chain | Residue |
| E | ASP179 |
| E | THR180 |
| E | GLY181 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue CL E 302 |
| Chain | Residue |
| E | LYS57 |
| E | LEU58 |
| site_id | AF3 |
| Number of Residues | 1 |
| Details | binding site for residue CL E 303 |
| Chain | Residue |
| E | ARG185 |
| site_id | AF4 |
| Number of Residues | 3 |
| Details | binding site for residue MPD E 304 |
| Chain | Residue |
| E | GLN206 |
| D | GLU259 |
| D | TYR274 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue CL F 301 |
| Chain | Residue |
| F | LEU127 |
| F | ARG192 |
| F | HOH402 |
| site_id | AF6 |
| Number of Residues | 1 |
| Details | binding site for residue CL F 302 |
| Chain | Residue |
| F | ALA191 |
| site_id | AF7 |
| Number of Residues | 2 |
| Details | binding site for residue CL G 301 |
| Chain | Residue |
| G | ARG185 |
| G | ALA191 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue MPD G 302 |
| Chain | Residue |
| A | ALA184 |
| A | GLU259 |
| A | SER261 |
| G | GLN206 |
| site_id | AF9 |
| Number of Residues | 3 |
| Details | binding site for residue CL H 301 |
| Chain | Residue |
| H | ARG185 |
| H | GLU190 |
| H | ALA191 |
| site_id | AG1 |
| Number of Residues | 3 |
| Details | binding site for residue CL H 302 |
| Chain | Residue |
| H | ASP179 |
| H | THR180 |
| H | GLY181 |
Functional Information from PROSITE/UniProt
| site_id | PS01316 |
| Number of Residues | 22 |
| Details | ATP_P_PHORIBOSYLTR ATP phosphoribosyltransferase signature. ElaplvGlGdlIvDVvdTGnTL |
| Chain | Residue | Details |
| E | GLU163-LEU184 |
