Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
| A | 0045454 | biological_process | cell redox homeostasis |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019430 | biological_process | removal of superoxide radicals |
| B | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | binding site for residue FAD A 1001 |
| Chain | Residue |
| A | GLY13 |
| A | SER42 |
| A | GLN43 |
| A | THR47 |
| A | VAL50 |
| A | ASN52 |
| A | VAL84 |
| A | ALA113 |
| A | THR114 |
| A | GLY115 |
| A | TRP130 |
| A | GLY14 |
| A | GLN131 |
| A | CYS140 |
| A | GLY282 |
| A | ASP283 |
| A | ARG290 |
| A | GLN291 |
| A | ALA292 |
| A | HOH1105 |
| A | HOH1106 |
| A | HOH1107 |
| A | GLY15 |
| A | HOH1109 |
| A | HOH1110 |
| A | HOH1111 |
| A | HOH1115 |
| A | PRO16 |
| A | ALA17 |
| A | PHE35 |
| A | VAL36 |
| A | HIS40 |
| A | THR41 |
| site_id | AC2 |
| Number of Residues | 30 |
| Details | binding site for residue FAD B 1001 |
| Chain | Residue |
| A | TYR24 |
| B | GLY13 |
| B | GLY14 |
| B | GLY15 |
| B | PRO16 |
| B | ALA17 |
| B | PHE35 |
| B | VAL36 |
| B | HIS40 |
| B | THR41 |
| B | SER42 |
| B | GLN43 |
| B | MET44 |
| B | THR47 |
| B | ASN52 |
| B | ASP83 |
| B | VAL84 |
| B | ALA113 |
| B | THR114 |
| B | GLY115 |
| B | GLY282 |
| B | ASP283 |
| B | ARG290 |
| B | GLN291 |
| B | ALA292 |
| B | ALA295 |
| B | HOH1103 |
| B | HOH1107 |
| B | HOH1109 |
| B | HOH1110 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue NA B 1002 |
| Chain | Residue |
| B | ARG5 |
| B | GLU82 |
| B | GLU103 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 21 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CavCDSam..AtgkeVvVVGGGD |
| Chain | Residue | Details |
| A | CYS137-ASP157 | |
