5M55

Nek2 bound to arylaminopurine 71

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue 7GG A 301

Chain	Residue
A	CYS22
A	VAL35
A	MET86
A	GLU87
A	TYR88
A	CYS89
A	ASP93
A	PHE148

---

site_id	AC2
Number of Residues	2
Details	binding site for residue SO4 A 302

Chain	Residue
A	TYR107
A	ARG105

---

site_id	AC3
Number of Residues	7
Details	binding site for residue SO4 A 303

Chain	Residue
A	HIS128
A	GLU195
A	LYS196
A	ILE199
A	SER261
A	VAL262
A	HOH401

---

site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 A 304

Chain	Residue
A	ARG234
A	ARG235
A	PRO237
A	TYR238
A	LEU266
A	HOH421
A	HOH484

---

site_id	AC5
Number of Residues	2
Details	binding site for residue CL A 305

Chain	Residue
A	ASN154
A	HIS277

---

Functional Information from PROSITE/UniProt

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpaNVFL

Chain	Residue	Details
A	VAL137-LEU149

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by autocatalysis","evidences":[{"source":"PubMed","id":"17197699","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by autocatalysis","evidences":[{"source":"PubMed","id":"17197699","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---