5M42

Structure of Thermus thermophilus L-proline dehydrogenase lacking alpha helices A, B and C

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004657	molecular_function	proline dehydrogenase activity
A	0006562	biological_process	L-proline catabolic process
A	0010133	biological_process	obsolete L-proline catabolic process to L-glutamate

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue FMN A 2001

Chain	Residue
A	ASP133
A	ALA225
A	THR226
A	HIS227
A	LEU254
A	TYR275
A	HOH2102
A	HOH2121
A	MET134
A	VAL161
A	GLN163
A	ARG184
A	VAL186
A	LYS187
A	GLY188
A	ALA189

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"evidences":[{"source":"PubMed","id":"18426222","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9RW55","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17344208","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18426222","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2EKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2G37","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17344208","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2G37","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Site: {"description":"Critical for catalytic activity","evidences":[{"source":"PubMed","id":"18426222","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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