5M10

Crystal structure of cyclohexanone monooxygenase from Thermocrispum municipale in the oxidised state with a bound nicotinamide.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
A	0018667	molecular_function	cyclohexanone monooxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	39
Details	binding site for residue FAD A 601

Chain	Residue
A	ILE14
A	TRP48
A	TRP50
A	TYR53
A	SER58
A	ASP59
A	THR60
A	TYR65
A	THR110
A	GLU111
A	VAL112
A	GLY15
A	ALA142
A	LEU143
A	GLY144
A	SER147
A	ARG329
A	ASN388
A	MET392
A	LEU428
A	ASN436
A	LEU437
A	GLY17
A	NAP602
A	NCA603
A	HOH725
A	HOH797
A	HOH890
A	HOH922
A	HOH929
A	HOH986
A	HOH992
A	HOH1000
A	PHE18
A	GLY19
A	GLU39
A	LYS40
A	GLY46
A	THR47

---

site_id	AC2
Number of Residues	38
Details	binding site for residue NAP A 602

Chain	Residue
A	LYS57
A	ASP59
A	LEU146
A	PRO152
A	ILE184
A	GLY185
A	THR186
A	GLY187
A	SER188
A	THR189
A	GLN192
A	ARG209
A	THR210
A	ARG329
A	ALA379
A	THR380
A	GLY381
A	PHE382
A	TRP492
A	FAD601
A	NCA603
A	HOH738
A	HOH752
A	HOH763
A	HOH765
A	HOH795
A	HOH807
A	HOH908
A	HOH909
A	HOH933
A	HOH944
A	HOH969
A	HOH976
A	HOH1019
A	HOH1022
A	HOH1081
A	HOH1087
A	HOH1137

---

site_id	AC3
Number of Residues	6
Details	binding site for residue NCA A 603

Chain	Residue
A	LEU146
A	ARG329
A	THR435
A	LEU437
A	FAD601
A	NAP602

---

site_id	AC4
Number of Residues	8
Details	binding site for residue TRS A 604

Chain	Residue
A	GLY42
A	ASN109
A	GLU132
A	GOL605
A	HOH736
A	HOH773
A	HOH822
A	HOH1064

---

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL A 605

Chain	Residue
A	ARG36
A	PHE38
A	GLN107
A	GLU132
A	TRS604

---

site_id	AC6
Number of Residues	9
Details	binding site for residue GOL A 606

Chain	Residue
A	ARG163
A	LEU164
A	HOH737
A	HOH861
A	HOH964
A	HOH979
A	ASP114
A	ILE116
A	GLY162

---

site_id	AC7
Number of Residues	8
Details	binding site for residue GOL A 607

Chain	Residue
A	VAL215
A	ILE310
A	ASN333
A	GLY335
A	TYR336
A	TYR337
A	GLU338
A	HOH878

---

site_id	AC8
Number of Residues	5
Details	binding site for residue TRS A 608

Chain	Residue
A	GLU294
A	PRO487
A	ASP490
A	ALA496
A	HOH1060

---

site_id	AC9
Number of Residues	5
Details	binding site for residue GOL A 609

Chain	Residue
A	GLU226
A	ASN233
A	ILE237
A	ARG528
A	HOH780

---

site_id	AD1
Number of Residues	6
Details	binding site for residue GOL A 610

Chain	Residue
A	GLU251
A	ALA272
A	LYS275
A	ARG280
A	GLY284
A	HOH856

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