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5LZJ

Cholera toxin El Tor B-pentamer in complex with inhibitor Laura237

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005534molecular_functiongalactose binding
A0005576cellular_componentextracellular region
A0016020cellular_componentmembrane
A0020002cellular_componenthost cell plasma membrane
A0035821biological_processmodulation of process of another organism
A0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
A0042597cellular_componentperiplasmic space
A0046812molecular_functionhost cell surface binding
A0090729molecular_functiontoxin activity
A1902494cellular_componentcatalytic complex
B0005515molecular_functionprotein binding
B0005534molecular_functiongalactose binding
B0005576cellular_componentextracellular region
B0016020cellular_componentmembrane
B0020002cellular_componenthost cell plasma membrane
B0035821biological_processmodulation of process of another organism
B0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
B0042597cellular_componentperiplasmic space
B0046812molecular_functionhost cell surface binding
B0090729molecular_functiontoxin activity
B1902494cellular_componentcatalytic complex
C0005515molecular_functionprotein binding
C0005534molecular_functiongalactose binding
C0005576cellular_componentextracellular region
C0016020cellular_componentmembrane
C0020002cellular_componenthost cell plasma membrane
C0035821biological_processmodulation of process of another organism
C0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
C0042597cellular_componentperiplasmic space
C0046812molecular_functionhost cell surface binding
C0090729molecular_functiontoxin activity
C1902494cellular_componentcatalytic complex
D0005515molecular_functionprotein binding
D0005534molecular_functiongalactose binding
D0005576cellular_componentextracellular region
D0016020cellular_componentmembrane
D0020002cellular_componenthost cell plasma membrane
D0035821biological_processmodulation of process of another organism
D0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
D0042597cellular_componentperiplasmic space
D0046812molecular_functionhost cell surface binding
D0090729molecular_functiontoxin activity
D1902494cellular_componentcatalytic complex
E0005515molecular_functionprotein binding
E0005534molecular_functiongalactose binding
E0005576cellular_componentextracellular region
E0016020cellular_componentmembrane
E0020002cellular_componenthost cell plasma membrane
E0035821biological_processmodulation of process of another organism
E0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
E0042597cellular_componentperiplasmic space
E0046812molecular_functionhost cell surface binding
E0090729molecular_functiontoxin activity
E1902494cellular_componentcatalytic complex
Functional Information from PDB Data
site_idAC1
Number of Residues9
Detailsbinding site for residue SO4 A 201
ChainResidue
ATYR12
AHIS13
ATRP88
AHOH301
AHOH309
ETYR12
EHIS13
EASN14
ETRP88

site_idAC2
Number of Residues3
Detailsbinding site for residue PEG B 201
ChainResidue
BGLU11
BTYR12
CARG35

site_idAC3
Number of Residues9
Detailsbinding site for residue PGE C 201
ChainResidue
BTHR78
BGLU79
BHOH303
BHOH374
CTYR76
CLEU77
CGLU79
CHOH316
CHOH341

site_idAC4
Number of Residues19
Detailsbinding site for residue 7BT C 202
ChainResidue
CHIS13
CASN14
CGLU51
CGLN56
CHIS57
CGLN61
CTRP88
CASN90
CLYS91
CHOH311
CHOH347
CHOH349
CHOH396
DHOH378
ETYR18
ETHR19
ELEU20
EASN44
EALA46

site_idAC5
Number of Residues10
Detailsbinding site for residue PGE D 201
ChainResidue
CTHR78
CGLU79
CASN103
DLYS23
DTYR76
DLEU77
DGLU79
DHOH322
DHOH337
DHOH369

site_idAC6
Number of Residues18
Detailsbinding site for residue 7BT D 202
ChainResidue
AILE17
ATYR18
ATHR19
AASN44
DHIS13
DASN14
DGLU51
DGLN56
DGLN61
DTRP88
DASN90
DLYS91
DHOH301
DHOH305
DHOH318
DHOH350
DHOH382
EHOH355

site_idAC7
Number of Residues4
Detailsbinding site for residue PEG E 201
ChainResidue
DGLU11
DTYR12
EARG35
EHOH360

222415

PDB entries from 2024-07-10

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