5LZH

Cholera toxin classical B-pentamer in complex with inhibitor PC262

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0046872	molecular_function	metal ion binding
B	0005576	cellular_component	extracellular region
B	0046872	molecular_function	metal ion binding
C	0005576	cellular_component	extracellular region
C	0046872	molecular_function	metal ion binding
D	0005576	cellular_component	extracellular region
D	0046872	molecular_function	metal ion binding
E	0005576	cellular_component	extracellular region
E	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue 7BN A 201

Chain	Residue
A	GLU11
A	ASN90
A	LYS91
A	HOH311
A	HOH316
A	HOH323
A	HOH331
A	HOH350
A	HOH358
A	HOH367
A	HOH369
A	TYR12
A	HOH372
B	GLY33
C	HOH321
A	HIS13
A	GLU51
A	GLN56
A	HIS57
A	ILE58
A	GLN61
A	TRP88

---

site_id	AC2
Number of Residues	22
Details	binding site for residue 7BN B 201

Chain	Residue
B	GLU11
B	TYR12
B	HIS13
B	GLU51
B	GLN56
B	HIS57
B	ILE58
B	GLN61
B	TRP88
B	ASN90
B	LYS91
B	HOH314
B	HOH318
B	HOH323
B	HOH325
B	HOH337
B	HOH338
B	HOH345
B	HOH356
B	HOH368
B	HOH371
C	GLY33

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MRD B 202

Chain	Residue
B	HIS13
D	ALA10
D	GLU11
D	TYR12
D	HIS13
D	7BN201

---

site_id	AC4
Number of Residues	23
Details	binding site for residue 7BN C 201

Chain	Residue
C	GLU11
C	TYR12
C	HIS13
C	GLU51
C	GLN56
C	GLN61
C	TRP88
C	ASN90
C	LYS91
C	HOH310
C	HOH311
C	HOH324
C	HOH331
C	HOH332
C	HOH333
C	HOH334
C	HOH344
C	HOH349
C	HOH354
C	HOH361
C	HOH367
D	GLY33
D	LYS34

---

site_id	AC5
Number of Residues	3
Details	binding site for residue CA C 202

Chain	Residue
B	GLU79
B	HOH303
C	GLU79

---

site_id	AC6
Number of Residues	4
Details	binding site for residue CA C 203

Chain	Residue
B	GLU79
B	HOH303
C	GLU79
C	HOH347

---

site_id	AC7
Number of Residues	22
Details	binding site for residue 7BN D 201

Chain	Residue
D	HOH360
D	HOH370
E	GLY33
A	HOH356
B	MRD202
B	HOH350
D	GLU11
D	TYR12
D	HIS13
D	GLU51
D	GLN56
D	GLN61
D	TRP88
D	ASN90
D	LYS91
D	HOH303
D	HOH324
D	HOH329
D	HOH338
D	HOH340
D	HOH347
D	HOH348

---

site_id	AC8
Number of Residues	6
Details	binding site for residue TRS D 202

Chain	Residue
D	THR78
D	ASN103
D	HOH321
D	HOH341
E	TYR76
E	LEU77

---

site_id	AC9
Number of Residues	24
Details	binding site for residue 7BN E 201

Chain	Residue
A	GLY33
A	LYS34
D	ILE58
E	GLU11
E	TYR12
E	HIS13
E	GLU51
E	GLN56
E	HIS57
E	ILE58
E	GLN61
E	TRP88
E	ASN90
E	LYS91
E	HOH304
E	HOH307
E	HOH313
E	HOH318
E	HOH325
E	HOH330
E	HOH339
E	HOH362
E	HOH371
E	HOH374

---

site_id	AD1
Number of Residues	4
Details	binding site for residue PEG E 202

Chain	Residue
E	THR41
E	PHE42
E	GLY45
E	HOH397

---

site_id	AD2
Number of Residues	3
Details	binding site for residue CA E 203

Chain	Residue
D	HOH321
D	HOH321
E	GLU79

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