5LXH
GABARAP-L1 ATG4B LIR Complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000045 | biological_process | autophagosome assembly |
| A | 0000421 | cellular_component | autophagosome membrane |
| A | 0000423 | biological_process | mitophagy |
| A | 0005515 | molecular_function | protein binding |
| A | 0005543 | molecular_function | phospholipid binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005776 | cellular_component | autophagosome |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005829 | cellular_component | cytosol |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005874 | cellular_component | microtubule |
| A | 0006914 | biological_process | autophagy |
| A | 0006995 | biological_process | cellular response to nitrogen starvation |
| A | 0008429 | molecular_function | phosphatidylethanolamine binding |
| A | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| A | 0030957 | molecular_function | Tat protein binding |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0031625 | molecular_function | ubiquitin protein ligase binding |
| A | 0048487 | molecular_function | beta-tubulin binding |
| A | 0050811 | molecular_function | GABA receptor binding |
| A | 0061723 | biological_process | glycophagy |
| A | 0097352 | biological_process | autophagosome maturation |
| B | 0000045 | biological_process | autophagosome assembly |
| B | 0000421 | cellular_component | autophagosome membrane |
| B | 0000423 | biological_process | mitophagy |
| B | 0005515 | molecular_function | protein binding |
| B | 0005543 | molecular_function | phospholipid binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005776 | cellular_component | autophagosome |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005829 | cellular_component | cytosol |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0005874 | cellular_component | microtubule |
| B | 0006914 | biological_process | autophagy |
| B | 0006995 | biological_process | cellular response to nitrogen starvation |
| B | 0008429 | molecular_function | phosphatidylethanolamine binding |
| B | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| B | 0030957 | molecular_function | Tat protein binding |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0031625 | molecular_function | ubiquitin protein ligase binding |
| B | 0048487 | molecular_function | beta-tubulin binding |
| B | 0050811 | molecular_function | GABA receptor binding |
| B | 0061723 | biological_process | glycophagy |
| B | 0097352 | biological_process | autophagosome maturation |
| C | 0000045 | biological_process | autophagosome assembly |
| C | 0000421 | cellular_component | autophagosome membrane |
| C | 0000423 | biological_process | mitophagy |
| C | 0005515 | molecular_function | protein binding |
| C | 0005543 | molecular_function | phospholipid binding |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005776 | cellular_component | autophagosome |
| C | 0005783 | cellular_component | endoplasmic reticulum |
| C | 0005794 | cellular_component | Golgi apparatus |
| C | 0005829 | cellular_component | cytosol |
| C | 0005856 | cellular_component | cytoskeleton |
| C | 0005874 | cellular_component | microtubule |
| C | 0006914 | biological_process | autophagy |
| C | 0006995 | biological_process | cellular response to nitrogen starvation |
| C | 0008429 | molecular_function | phosphatidylethanolamine binding |
| C | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| C | 0030957 | molecular_function | Tat protein binding |
| C | 0031410 | cellular_component | cytoplasmic vesicle |
| C | 0031625 | molecular_function | ubiquitin protein ligase binding |
| C | 0048487 | molecular_function | beta-tubulin binding |
| C | 0050811 | molecular_function | GABA receptor binding |
| C | 0061723 | biological_process | glycophagy |
| C | 0097352 | biological_process | autophagosome maturation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | ASP45 |
| A | LYS46 |
| A | ARG47 |
| A | LYS48 |
| A | HOH303 |
| A | HOH341 |
| B | HIS69 |
| E | ASP387 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | ASP45 |
| B | LYS46 |
| B | ARG47 |
| B | LYS48 |
| B | SO4203 |
| B | HOH333 |
| F | ASP387 |
| A | HIS69 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 202 |
| Chain | Residue |
| B | ARG14 |
| C | GLU101 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 203 |
| Chain | Residue |
| B | TYR5 |
| B | ASP8 |
| B | HIS9 |
| B | LYS48 |
| B | SO4201 |
| B | HOH311 |
| B | HOH319 |
| C | THR83 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 204 |
| Chain | Residue |
| B | PHE79 |
| B | VAL80 |
| B | ASN81 |
| B | ASN82 |
| B | TYR106 |
| B | ALA108 |
| B | HOH302 |
| B | HOH315 |
| B | HOH363 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 205 |
| Chain | Residue |
| A | HOH315 |
| B | ARG22 |
| B | GLU96 |
| B | TYR103 |
| B | HOH301 |
| B | HOH334 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 201 |
| Chain | Residue |
| A | GLN93 |
| A | GLU96 |
| C | LYS46 |
| C | ARG47 |
| C | LYS48 |
| C | SO4202 |
| C | HOH302 |
| G | ASP387 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 202 |
| Chain | Residue |
| C | TYR5 |
| C | ASP8 |
| C | HIS9 |
| C | LYS48 |
| C | SO4201 |
| C | HOH302 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 203 |
| Chain | Residue |
| C | ARG71 |
| C | GLU73 |
| C | ASP74 |
| C | SER113 |
| C | VAL114 |
| C | TYR115 |
| C | GLY116 |
| C | LYS117 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 204 |
| Chain | Residue |
| C | GLU34 |
| C | LYS35 |
| C | ARG47 |
| C | HOH310 |
| C | HOH334 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Propeptide: {"description":"Removed in mature form","featureId":"PRO_0000420208","evidences":[{"source":"PubMed","id":"20404487","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"(Microbial infection) Cleavage; by RavZ","evidences":[{"source":"PubMed","id":"23112293","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by ATG4B","evidences":[{"source":"PubMed","id":"20404487","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Lipidation: {"description":"Phosphatidylserine amidated glycine; alternate","evidences":[{"source":"PubMed","id":"33909989","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | Motif: {"description":"LIR","evidences":[{"source":"PubMed","id":"28287329","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"26378241","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
