Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 401 |
| Chain | Residue |
| A | SER233 |
| A | ALA237 |
| A | HOH508 |
| A | HOH716 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 402 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue TFA A 403 |
| Chain | Residue |
| A | PHE253 |
| A | PRO254 |
| A | SER288 |
| A | SER289 |
| A | HOH526 |
| A | HOH546 |
| A | HOH674 |
| A | GLY241 |
| A | LYS243 |
| A | VAL252 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue TFA A 404 |
| Chain | Residue |
| A | PHE130 |
| A | SER131 |
| A | PHE145 |
| A | ASP146 |
| A | LYS149 |
| A | HOH537 |
| A | HOH654 |
| A | HOH710 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | VAL272 |
| A | TYR277 |
| A | ALA312 |
| A | SER329 |
| A | LYS330 |
| A | HOH606 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | TYR202 |
| A | ALA203 |
| A | VAL204 |
| A | GLY207 |
| A | THR208 |
| A | LYS210 |
| A | HOH502 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue ACT A 407 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| A | PRO282 |
| A | CYS290 |
| A | HOH503 |
| A | HOH507 |
| A | HOH801 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 408 |
| Chain | Residue |
| A | GLY167 |
| A | THR168 |
| A | HOH513 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP35 | |
| A | SER199 | |
