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5LVR

Crystal structure of human PCAF bromodomain in complex with compound-E (CPD-E)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004402molecular_functionhistone acetyltransferase activity
B0004402molecular_functionhistone acetyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue EDO A 901
ChainResidue
ALYS733
AGLN737
ASER774
ALEU777
AHOH1004

site_idAC2
Number of Residues4
Detailsbinding site for residue EDO A 902
ChainResidue
ATYR729
ALYS778
AARG780
BARG776

site_idAC3
Number of Residues7
Detailsbinding site for residue EDO A 903
ChainResidue
AGLN743
ATRP746
AGLU808
ACYS812
BGLN738
BLYS823
BHOH1039

site_idAC4
Number of Residues6
Detailsbinding site for residue 78Y A 904
ChainResidue
APRO747
AGLU756
AASN803
ATYR809
AHOH1003
BGLN737

site_idAC5
Number of Residues5
Detailsbinding site for residue EDO B 901
ChainResidue
BVAL752
BLYS753
BARG754
BTYR761
BHOH1044

site_idAC6
Number of Residues8
Detailsbinding site for residue EDO B 902
ChainResidue
AGLU750
BLYS740
BHIS742
BGLN743
BALA745
BTRP746
BMET749
BHOH1003

site_idAC7
Number of Residues4
Detailsbinding site for residue EDO B 903
ChainResidue
BPRO747
BGLU756
BTYR809
BDMS904

site_idAC8
Number of Residues4
Detailsbinding site for residue DMS B 904
ChainResidue
BPRO747
BASN803
BEDO903
BHOH1005

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues58
DetailsBROMODOMAIN_1 Bromodomain signature. AwpFmepvKrteap..GYYevIrfpMdlktMserlknry..Yvskklfmadlqr.VftNCkeY
ChainResidueDetails
AALA745-TYR802

226707

PDB entries from 2024-10-30

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