5LUL

Structure of a triple variant of cutinase 2 from Thermobifida cellulosilytica

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0042597	cellular_component	periplasmic space
A	0050525	molecular_function	cutinase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity
B	0005576	cellular_component	extracellular region
B	0042597	cellular_component	periplasmic space
B	0050525	molecular_function	cutinase activity
B	0052689	molecular_function	carboxylic ester hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 301

Chain	Residue
A	ARG32
A	ALA35
A	PHE38
A	HOH503
A	HOH541
A	HOH568

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site_id	AC2
Number of Residues	2
Details	binding site for residue CL B 301

Chain	Residue
B	ASN191
B	ARG257

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Functional Information from PROSITE/UniProt

site_id	PS00120
Number of Residues	10
Details	LIPASE_SER Lipases, serine active site. LAVMGHSMGG

Chain	Residue	Details
A	LEU125-GLY134

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:Q47RJ6

Chain	Residue	Details
A	SER131
B	SER131

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Charge relay system => ECO:0000250|UniProtKB:A0A0K8P6T7

Chain	Residue	Details
A	ASP177
A	HIS209
B	ASP177
B	HIS209

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A0A0K8P6T7

Chain	Residue	Details
A	TYR61
A	MET132
A	TRP156
B	TYR61
B	MET132
B	TRP156

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