5LTL

Structure of human chemokine CCL16

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005125	molecular_function	cytokine activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006935	biological_process	chemotaxis
A	0006954	biological_process	inflammatory response
A	0006955	biological_process	immune response
A	0007154	biological_process	cell communication
A	0007267	biological_process	cell-cell signaling
A	0008009	molecular_function	chemokine activity
A	0030335	biological_process	positive regulation of cell migration
A	0042056	molecular_function	chemoattractant activity
A	0048020	molecular_function	CCR chemokine receptor binding
A	0048245	biological_process	eosinophil chemotaxis
A	0050918	biological_process	positive chemotaxis
A	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
A	0070098	biological_process	chemokine-mediated signaling pathway
B	0005125	molecular_function	cytokine activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006935	biological_process	chemotaxis
B	0006954	biological_process	inflammatory response
B	0006955	biological_process	immune response
B	0007154	biological_process	cell communication
B	0007267	biological_process	cell-cell signaling
B	0008009	molecular_function	chemokine activity
B	0030335	biological_process	positive regulation of cell migration
B	0042056	molecular_function	chemoattractant activity
B	0048020	molecular_function	CCR chemokine receptor binding
B	0048245	biological_process	eosinophil chemotaxis
B	0050918	biological_process	positive chemotaxis
B	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
B	0070098	biological_process	chemokine-mediated signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue NA A 101

Chain	Residue
A	ILE65
A	ASP67
A	LEU70
A	HOH209
A	HOH227
A	HOH231

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site_id	AC2
Number of Residues	3
Details	binding site for residue GOL B 101

Chain	Residue
A	GLN62
B	TYR31
B	ILE65

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Functional Information from PROSITE/UniProt

site_id	PS00472
Number of Residues	41
Details	SMALL_CYTOKINES_CC Small cytokines (intercrine/chemokine) C-C subfamily signature. CCLkyyekv..LprrlVvgYrkaln...Chlp.AIIFvtkrnrev.CT

Chain	Residue	Details
A	CYS14-THR54

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