5LT2

nucleotide-free kinesin-1 motor domain, P1 crystal form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003777	molecular_function	microtubule motor activity
A	0005524	molecular_function	ATP binding
A	0007018	biological_process	microtubule-based movement
A	0008017	molecular_function	microtubule binding
B	0003777	molecular_function	microtubule motor activity
B	0005524	molecular_function	ATP binding
B	0007018	biological_process	microtubule-based movement
B	0008017	molecular_function	microtubule binding
C	0003777	molecular_function	microtubule motor activity
C	0005524	molecular_function	ATP binding
C	0007018	biological_process	microtubule-based movement
C	0008017	molecular_function	microtubule binding
D	0003777	molecular_function	microtubule motor activity
D	0005524	molecular_function	ATP binding
D	0007018	biological_process	microtubule-based movement
D	0008017	molecular_function	microtubule binding
E	0003777	molecular_function	microtubule motor activity
E	0005524	molecular_function	ATP binding
E	0007018	biological_process	microtubule-based movement
E	0008017	molecular_function	microtubule binding
K	0003777	molecular_function	microtubule motor activity
K	0005524	molecular_function	ATP binding
K	0007018	biological_process	microtubule-based movement
K	0008017	molecular_function	microtubule binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 401

Chain	Residue
A	SER88
A	SER89
A	GLY90
A	LYS91
A	THR92
A	HOH518

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 B 401

Chain	Residue
B	LYS91
B	THR92
B	SER88
B	SER89
B	GLY90

---

site_id	AC3
Number of Residues	8
Details	binding site for residue SO4 C 401

Chain	Residue
C	GLN86
C	SER88
C	SER89
C	GLY90
C	LYS91
C	THR92
C	HOH514
C	HOH532

---

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 C 402

Chain	Residue
C	SER133
C	VAL165
C	GLU170
C	HOH502

---

site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 C 403

Chain	Residue
A	LYS150
C	LYS141
C	THR151
C	HOH508
C	HOH546

---

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 D 401

Chain	Residue
D	SER88
D	SER89
D	GLY90
D	LYS91
D	THR92

---

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 D 402

Chain	Residue
D	TYR274
D	VAL275
D	PRO276
D	TYR277
D	ARG278

---

site_id	AC8
Number of Residues	5
Details	binding site for residue SO4 D 403

Chain	Residue
B	TYR77
B	ASN78
B	ASP288
B	ASN293
D	HOH501

---

site_id	AC9
Number of Residues	5
Details	binding site for residue SO4 E 401

Chain	Residue
E	SER88
E	SER89
E	GLY90
E	LYS91
E	THR92

---

site_id	AD1
Number of Residues	6
Details	binding site for residue SO4 K 401

Chain	Residue
K	SER88
K	SER89
K	GLY90
K	LYS91
K	THR92
K	HOH519

---

site_id	AD2
Number of Residues	6
Details	binding site for residue SO4 K 402

Chain	Residue
A	GLU75
A	TYR77
K	GLU75
K	GLY76
K	TYR77
K	HOH513

---

Functional Information from PROSITE/UniProt

site_id	PS00411
Number of Residues	12
Details	KINESIN_MOTOR_1 Kinesin motor domain signature. GKLyLVDLAGSE

Chain	Residue	Details
A	GLY225-GLU236

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING:

Chain	Residue	Details
A	GLY85
B	GLY85
C	GLY85
D	GLY85
E	GLY85
K	GLY85

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	MOD_RES: N-acetylalanine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378

Chain	Residue	Details
A	ALA2
B	ALA2
C	ALA2
D	ALA2
E	ALA2
K	ALA2

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS213
K	LYS213
B	LYS213
C	LYS213
D	LYS213
E	LYS213

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