5LSE
PHOTOSYNTHETIC REACTION CENTER MUTANT WITH Glu L212 replaced with Ala (CHAIN L, EL212W), Asp L213 replaced with ALA (Chain L, DL213A) AND LEU M215 REPLACED WITH ALA (CHAIN M, LM215A)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| H | 0015979 | biological_process | photosynthesis |
| H | 0016020 | cellular_component | membrane |
| H | 0019684 | biological_process | photosynthesis, light reaction |
| H | 0030077 | cellular_component | plasma membrane light-harvesting complex |
| H | 0042314 | molecular_function | bacteriochlorophyll binding |
| H | 0042717 | cellular_component | plasma membrane-derived chromatophore membrane |
| H | 0045156 | molecular_function | electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity |
| L | 0009772 | biological_process | photosynthetic electron transport in photosystem II |
| L | 0015979 | biological_process | photosynthesis |
| L | 0016020 | cellular_component | membrane |
| L | 0019684 | biological_process | photosynthesis, light reaction |
| L | 0030077 | cellular_component | plasma membrane light-harvesting complex |
| L | 0042314 | molecular_function | bacteriochlorophyll binding |
| L | 0042717 | cellular_component | plasma membrane-derived chromatophore membrane |
| L | 0045156 | molecular_function | electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity |
| L | 0046872 | molecular_function | metal ion binding |
| M | 0009772 | biological_process | photosynthetic electron transport in photosystem II |
| M | 0015979 | biological_process | photosynthesis |
| M | 0016020 | cellular_component | membrane |
| M | 0019684 | biological_process | photosynthesis, light reaction |
| M | 0030077 | cellular_component | plasma membrane light-harvesting complex |
| M | 0042314 | molecular_function | bacteriochlorophyll binding |
| M | 0042717 | cellular_component | plasma membrane-derived chromatophore membrane |
| M | 0045156 | molecular_function | electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity |
| M | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue BCL L 301 |
| Chain | Residue |
| L | PHE97 |
| L | HIS168 |
| L | HIS173 |
| L | ALA176 |
| L | ILE177 |
| L | PHE180 |
| L | SER244 |
| L | CYS247 |
| L | MET248 |
| L | BCL302 |
| L | BPH303 |
| L | ALA124 |
| M | TYR210 |
| M | BCL402 |
| L | ILE125 |
| L | ALA127 |
| L | LEU131 |
| L | VAL157 |
| L | TYR162 |
| L | ASN166 |
| L | PHE167 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue BCL L 302 |
| Chain | Residue |
| L | ILE46 |
| L | TYR128 |
| L | LEU131 |
| L | PHE146 |
| L | ILE150 |
| L | HIS153 |
| L | LEU154 |
| L | BCL301 |
| L | BPH303 |
| M | PHE197 |
| M | GLY203 |
| M | ILE206 |
| M | ALA207 |
| M | TYR210 |
| M | LEU214 |
| M | LDA406 |
| M | HOH515 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue BPH L 303 |
| Chain | Residue |
| L | ALA93 |
| L | PHE97 |
| L | TRP100 |
| L | GLU104 |
| L | ILE117 |
| L | ALA120 |
| L | PHE121 |
| L | ALA124 |
| L | VAL241 |
| L | BCL301 |
| L | BCL302 |
| M | TYR210 |
| M | ALA213 |
| M | LEU214 |
| M | TRP252 |
| M | MET256 |
| M | U10404 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue U10 L 304 |
| Chain | Residue |
| L | HIS190 |
| L | LEU193 |
| L | PHE216 |
| L | TYR222 |
| L | SER223 |
| L | ILE224 |
| L | GLY225 |
| L | THR226 |
| L | ILE229 |
| L | TRP263 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue D12 L 305 |
| Chain | Residue |
| H | HOH501 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue FE L 306 |
| Chain | Residue |
| L | HIS190 |
| L | HIS230 |
| M | HIS219 |
| M | GLU234 |
| M | HIS266 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for residue BCL M 401 |
| Chain | Residue |
| L | HIS168 |
| L | MET174 |
| L | ILE177 |
| L | SER178 |
| L | THR182 |
| L | HOH408 |
| M | MET122 |
| M | ILE179 |
| M | HIS182 |
| M | LEU183 |
| M | THR186 |
| M | BCL402 |
| M | BPH403 |
| M | SPN405 |
| site_id | AC8 |
| Number of Residues | 20 |
| Details | binding site for residue BCL M 402 |
| Chain | Residue |
| M | TYR210 |
| M | VAL276 |
| M | GLY280 |
| M | ILE284 |
| M | BCL401 |
| M | BPH403 |
| L | VAL157 |
| L | TYR162 |
| L | PHE181 |
| L | BCL301 |
| M | LEU156 |
| M | LEU160 |
| M | THR186 |
| M | ASN187 |
| M | SER190 |
| M | LEU196 |
| M | PHE197 |
| M | HIS202 |
| M | SER205 |
| M | ILE206 |
| site_id | AC9 |
| Number of Residues | 19 |
| Details | binding site for residue BPH M 403 |
| Chain | Residue |
| L | PHE181 |
| L | ALA184 |
| L | LEU185 |
| L | LEU189 |
| L | LEU219 |
| M | LEU60 |
| M | GLY63 |
| M | PHE67 |
| M | ALA125 |
| M | VAL126 |
| M | TRP129 |
| M | THR133 |
| M | THR146 |
| M | ALA149 |
| M | PHE150 |
| M | ALA153 |
| M | THR277 |
| M | BCL401 |
| M | BCL402 |
| site_id | AD1 |
| Number of Residues | 14 |
| Details | binding site for residue U10 M 404 |
| Chain | Residue |
| L | GLY35 |
| L | BPH303 |
| M | MET218 |
| M | HIS219 |
| M | THR222 |
| M | ALA248 |
| M | ALA249 |
| M | TRP252 |
| M | MET256 |
| M | ASN259 |
| M | ALA260 |
| M | THR261 |
| M | ILE265 |
| M | TRP268 |
| site_id | AD2 |
| Number of Residues | 13 |
| Details | binding site for residue SPN M 405 |
| Chain | Residue |
| M | PHE67 |
| M | PHE68 |
| M | ILE70 |
| M | GLY71 |
| M | TRP75 |
| M | TRP115 |
| M | SER119 |
| M | TRP157 |
| M | MET158 |
| M | GLY161 |
| M | TRP171 |
| M | HIS182 |
| M | BCL401 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue LDA M 406 |
| Chain | Residue |
| H | TRP21 |
| H | LDA301 |
| H | HOH501 |
| L | BCL302 |
| M | PRO200 |
| M | GLY203 |
| M | LEU204 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue LDA M 407 |
| Chain | Residue |
| H | LDA301 |
| L | PRO28 |
| M | GLY257 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 M 408 |
| Chain | Residue |
| M | ASN28 |
| M | GLY53 |
| M | SER54 |
| M | HOH508 |
| M | HOH545 |
| site_id | AD6 |
| Number of Residues | 10 |
| Details | binding site for residue CDL M 409 |
| Chain | Residue |
| H | TYR30 |
| L | ASN199 |
| M | GLY143 |
| M | LYS144 |
| M | HIS145 |
| M | TRP148 |
| M | ARG267 |
| M | TRP271 |
| M | VAL274 |
| M | HOH562 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue LDA H 301 |
| Chain | Residue |
| H | GLN32 |
| H | TYR40 |
| M | ARG253 |
| M | PHE258 |
| M | LDA406 |
| M | LDA407 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue D12 H 302 |
| Chain | Residue |
| H | ALA25 |
| H | D12303 |
| H | D12305 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue D12 H 303 |
| Chain | Residue |
| H | D12302 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue D12 H 305 |
| Chain | Residue |
| H | D12302 |
Functional Information from PROSITE/UniProt
| site_id | PS00244 |
| Number of Residues | 27 |
| Details | REACTION_CENTER Photosynthetic reaction center proteins signature. NlfynPfHglSiaflygsalafAmHGA |
| Chain | Residue | Details |
| M | ASN195-ALA221 | |
| L | ASN166-ALA192 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | TOPO_DOM: Periplasmic |
| Chain | Residue | Details |
| H | MET1-ASP11 | |
| M | LYS110-ALA139 | |
| M | MET142-LEU167 | |
| M | PHE197-ALA225 | |
| M | ASN259-LEU285 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical |
| Chain | Residue | Details |
| H | LEU12-LEU31 | |
| M | HIS202 | |
| L | HIS116-MET138 | |
| L | PRO171-ALA198 | |
| L | GLY225-ILE250 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 228 |
| Details | TOPO_DOM: Cytoplasmic |
| Chain | Residue | Details |
| H | GLN32-ALA260 | |
| M | GLU234 | |
| M | TRP252 | |
| M | HIS266 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| L | HIS153 | |
| L | HIS173 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| L | HIS190 | |
| L | PHE216 | |
| L | HIS230 |
