Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0006584 | biological_process | catecholamine metabolic process |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0016206 | molecular_function | catechol O-methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 301 |
| Chain | Residue |
| A | ASP191 |
| A | ASP219 |
| A | ASN220 |
| A | DNC304 |
| A | HOH433 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 302 |
| Chain | Residue |
| A | HOH573 |
| A | ASP94 |
| A | LYS95 |
| A | TYR250 |
| A | HOH456 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue SAM A 303 |
| Chain | Residue |
| A | MET90 |
| A | ASN91 |
| A | VAL92 |
| A | GLY116 |
| A | ALA117 |
| A | TYR118 |
| A | TYR121 |
| A | SER122 |
| A | ILE139 |
| A | GLU140 |
| A | ILE141 |
| A | GLY167 |
| A | ALA168 |
| A | SER169 |
| A | GLN170 |
| A | ASP191 |
| A | HIS192 |
| A | TRP193 |
| A | DNC304 |
| A | HOH430 |
| A | HOH523 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue DNC A 304 |
| Chain | Residue |
| A | TRP88 |
| A | ASP191 |
| A | HIS192 |
| A | TRP193 |
| A | LYS194 |
| A | ASP219 |
| A | ASN220 |
| A | LEU248 |
| A | GLU249 |
| A | MG301 |
| A | SAM303 |
| A | HOH433 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP191 | |
| A | VAL92 | |
| A | SER122 | |
| A | GLU140 | |
| Chain | Residue | Details |
| A | ILE141 | |
| A | SER169 | |
| A | GLU114 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS194 | |
| A | ASN220 | |
| A | GLU249 | |
| A | GLY167 | |
| Chain | Residue | Details |
| A | ASP219 | |
| Chain | Residue | Details |
| A | SER267 | |
