Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004181 | molecular_function | metallocarboxypeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008270 | molecular_function | zinc ion binding |
B | 0004181 | molecular_function | metallocarboxypeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0008270 | molecular_function | zinc ion binding |
C | 0004181 | molecular_function | metallocarboxypeptidase activity |
C | 0006508 | biological_process | proteolysis |
C | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 401 |
Chain | Residue |
A | HIS69 |
A | GLU72 |
A | HIS196 |
F | 73N1 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue ZN B 401 |
Chain | Residue |
B | HIS69 |
B | GLU72 |
B | HIS196 |
B | HOH509 |
G | 73N1 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue ZN C 401 |
Chain | Residue |
C | HIS69 |
C | GLU72 |
C | HIS196 |
C | HOH503 |
H | 73N1 |
site_id | AC4 |
Number of Residues | 25 |
Details | binding site for Di-peptide 73N F 1 and DLY F 2 |
Chain | Residue |
A | HIS69 |
A | ARG71 |
A | ARG127 |
A | ASN144 |
A | ARG145 |
A | TYR198 |
A | SER199 |
A | SER207 |
A | TYR248 |
A | ALA250 |
A | GLY253 |
A | ASP255 |
A | THR268 |
A | GLU270 |
A | PHE279 |
A | ZN401 |
A | HOH559 |
A | HOH611 |
A | HOH678 |
F | VAL3 |
F | 73O4 |
F | MAA5 |
F | PHE6 |
F | HOH104 |
F | HOH106 |
site_id | AC5 |
Number of Residues | 16 |
Details | binding site for Di-peptide DLY F 2 and VAL F 3 |
Chain | Residue |
A | ARG71 |
A | ARG127 |
A | ARG145 |
A | GLU163 |
A | THR164 |
A | TYR198 |
A | SER199 |
A | TYR248 |
A | PHE279 |
A | HOH559 |
F | 73N1 |
F | 73O4 |
F | MAA5 |
F | PHE6 |
F | HOH104 |
F | HOH106 |
site_id | AC6 |
Number of Residues | 15 |
Details | binding site for Di-peptide DLY F 2 and PHE F 6 |
Chain | Residue |
A | ARG71 |
A | ARG127 |
A | TYR198 |
A | SER199 |
A | TYR248 |
A | PHE279 |
A | HOH559 |
F | 73N1 |
F | VAL3 |
F | 73O4 |
F | MAA5 |
F | HOH101 |
F | HOH103 |
F | HOH104 |
F | HOH106 |
site_id | AC7 |
Number of Residues | 17 |
Details | binding site for Di-peptide VAL F 3 and 73O F 4 |
Chain | Residue |
A | GLU16 |
A | ARG71 |
A | MET125 |
A | ARG127 |
A | ARG145 |
A | GLU163 |
A | THR164 |
A | TYR248 |
A | HOH510 |
F | 73N1 |
F | DLY2 |
F | MAA5 |
F | PHE6 |
F | HOH102 |
F | HOH105 |
F | HOH107 |
F | HOH109 |
site_id | AC8 |
Number of Residues | 13 |
Details | binding site for residues 73O F 4 and MAA F 5 |
Chain | Residue |
F | HOH109 |
A | GLU16 |
A | ARG71 |
A | MET125 |
A | GLU163 |
A | HOH510 |
F | DLY2 |
F | VAL3 |
F | PHE6 |
F | HOH102 |
F | HOH105 |
F | HOH106 |
F | HOH107 |
site_id | AC9 |
Number of Residues | 6 |
Details | binding site for Di-peptide MAA F 5 and PHE F 6 |
Chain | Residue |
F | DLY2 |
F | VAL3 |
F | 73O4 |
F | HOH101 |
F | HOH103 |
F | HOH106 |
site_id | AD1 |
Number of Residues | 24 |
Details | binding site for Di-peptide 73N G 1 and DLY G 2 |
Chain | Residue |
B | HIS69 |
B | ARG71 |
B | ARG127 |
B | ASN144 |
B | ARG145 |
B | TYR198 |
B | SER199 |
B | SER207 |
B | TYR248 |
B | GLY253 |
B | ASP255 |
B | GLU270 |
B | PHE279 |
B | ZN401 |
B | HOH509 |
B | HOH539 |
B | HOH681 |
B | HOH710 |
B | HOH761 |
B | HOH783 |
G | VAL3 |
G | 73O4 |
G | MAA5 |
G | PHE6 |
site_id | AD2 |
Number of Residues | 16 |
Details | binding site for Di-peptide DLY G 2 and VAL G 3 |
Chain | Residue |
B | ARG71 |
B | ARG127 |
B | ARG145 |
B | GLU163 |
B | TYR198 |
B | SER199 |
B | TYR248 |
B | PHE279 |
B | HOH509 |
B | HOH539 |
B | HOH761 |
B | HOH783 |
G | 73N1 |
G | 73O4 |
G | MAA5 |
G | PHE6 |
site_id | AD3 |
Number of Residues | 17 |
Details | binding site for Di-peptide DLY G 2 and PHE G 6 |
Chain | Residue |
B | ARG71 |
B | ARG127 |
B | TYR198 |
B | SER199 |
B | TYR248 |
B | PHE279 |
B | HOH509 |
B | HOH539 |
B | HOH587 |
B | HOH761 |
B | HOH783 |
C | LEU308 |
G | 73N1 |
G | VAL3 |
G | 73O4 |
G | MAA5 |
G | HOH102 |
site_id | AD4 |
Number of Residues | 16 |
Details | binding site for Di-peptide VAL G 3 and 73O G 4 |
Chain | Residue |
B | GLU16 |
B | ARG71 |
B | MET125 |
B | ARG127 |
B | ARG145 |
B | GLU163 |
B | TYR248 |
B | HOH503 |
B | HOH937 |
G | 73N1 |
G | DLY2 |
G | MAA5 |
G | PHE6 |
G | HOH101 |
G | HOH103 |
G | HOH104 |
site_id | AD5 |
Number of Residues | 13 |
Details | binding site for residues 73O G 4 and MAA G 5 |
Chain | Residue |
B | GLU16 |
B | ARG71 |
B | MET125 |
B | GLU163 |
B | HOH503 |
B | HOH937 |
G | DLY2 |
G | VAL3 |
G | PHE6 |
G | HOH101 |
G | HOH103 |
G | HOH104 |
G | HOH113 |
site_id | AD6 |
Number of Residues | 7 |
Details | binding site for Di-peptide MAA G 5 and PHE G 6 |
Chain | Residue |
B | HOH587 |
C | LEU308 |
G | DLY2 |
G | VAL3 |
G | 73O4 |
G | HOH102 |
G | HOH113 |
site_id | AD7 |
Number of Residues | 24 |
Details | binding site for Di-peptide 73N H 1 and DLY H 2 |
Chain | Residue |
C | HIS69 |
C | ARG71 |
C | ARG127 |
C | ASN144 |
C | ARG145 |
C | SER197 |
C | TYR198 |
C | SER207 |
C | TYR248 |
C | ALA250 |
C | GLY253 |
C | ASP255 |
C | GLU270 |
C | PHE279 |
C | ZN401 |
C | HOH503 |
C | HOH514 |
C | HOH597 |
C | HOH693 |
H | VAL3 |
H | 73O4 |
H | MAA5 |
H | PHE6 |
H | HOH703 |
site_id | AD8 |
Number of Residues | 14 |
Details | binding site for Di-peptide DLY H 2 and PHE H 6 |
Chain | Residue |
C | ARG71 |
C | ARG127 |
C | SER197 |
C | TYR198 |
C | TYR248 |
C | PHE279 |
C | HOH503 |
C | HOH519 |
H | 73N1 |
H | VAL3 |
H | 73O4 |
H | MAA5 |
H | HOH703 |
H | HOH704 |
site_id | AD9 |
Number of Residues | 15 |
Details | binding site for Di-peptide DLY H 2 and VAL H 3 |
Chain | Residue |
C | ARG71 |
C | ARG127 |
C | ARG145 |
C | GLU163 |
C | THR164 |
C | SER197 |
C | TYR198 |
C | TYR248 |
C | PHE279 |
C | HOH503 |
H | 73N1 |
H | 73O4 |
H | MAA5 |
H | PHE6 |
H | HOH703 |
site_id | AE1 |
Number of Residues | 16 |
Details | binding site for Di-peptide VAL H 3 and 73O H 4 |
Chain | Residue |
C | TRP15 |
C | GLU16 |
C | ARG71 |
C | MET125 |
C | ARG127 |
C | ARG145 |
C | GLU163 |
C | THR164 |
C | TYR248 |
C | HOH507 |
C | HOH789 |
H | 73N1 |
H | DLY2 |
H | MAA5 |
H | PHE6 |
H | HOH701 |
site_id | AE2 |
Number of Residues | 12 |
Details | binding site for residues 73O H 4 and MAA H 5 |
Chain | Residue |
C | TRP15 |
C | GLU16 |
C | ARG71 |
C | MET125 |
C | GLU163 |
C | HOH507 |
C | HOH789 |
H | DLY2 |
H | VAL3 |
H | PHE6 |
H | HOH701 |
H | HOH702 |
site_id | AE3 |
Number of Residues | 6 |
Details | binding site for Di-peptide MAA H 5 and PHE H 6 |
Chain | Residue |
C | HOH519 |
H | DLY2 |
H | VAL3 |
H | 73O4 |
H | HOH702 |
H | HOH704 |
Functional Information from PROSITE/UniProt
site_id | PS00132 |
Number of Residues | 23 |
Details | CARBOXYPEPT_ZN_1 Zinc carboxypeptidases, zinc-binding region 1 signature. PaIfMdcGfHArEwISHafcqwF |
Chain | Residue | Details |
A | PRO60-PHE82 | |
site_id | PS00133 |
Number of Residues | 11 |
Details | CARBOXYPEPT_ZN_2 Zinc carboxypeptidases, zinc-binding region 2 signature. HSYSQMIlYPY |
Chain | Residue | Details |
A | HIS196-TYR206 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU270 | |
B | GLU270 | |
C | GLU270 | |
Chain | Residue | Details |
A | HIS69 | |
A | GLU72 | |
A | HIS196 | |
B | HIS69 | |
B | GLU72 | |
B | HIS196 | |
C | HIS69 | |
C | GLU72 | |
C | HIS196 | |
Chain | Residue | Details |
A | ARG127 | |
C | ASN144 | |
C | SER197 | |
C | TYR248 | |
A | ASN144 | |
A | SER197 | |
A | TYR248 | |
B | ARG127 | |
B | ASN144 | |
B | SER197 | |
B | TYR248 | |
C | ARG127 | |