Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015293 | molecular_function | symporter activity |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 601 |
| Chain | Residue |
| A | THR376 |
| A | MET379 |
| A | SER417 |
| A | ILE418 |
| A | ALA420 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue ASP A 602 |
| Chain | Residue |
| A | ALA421 |
| A | GLY422 |
| A | ILE423 |
| A | PRO424 |
| A | ALA426 |
| A | GLY427 |
| A | ASP456 |
| A | ARG459 |
| A | THR460 |
| A | ASN463 |
| A | SER343 |
| A | SER344 |
| A | SER345 |
| A | THR382 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue 6Z6 A 603 |
| Chain | Residue |
| A | ALA113 |
| A | SER116 |
| A | GLY117 |
| A | GLY120 |
| A | ALA123 |
| A | VAL124 |
| A | TYR127 |
| A | ILE231 |
| A | ILE235 |
| A | PHE369 |
| A | VAL373 |
| A | ILE377 |
Functional Information from PROSITE/UniProt
| site_id | PS00713 |
| Number of Residues | 15 |
| Details | NA_DICARBOXYL_SYMP_1 Sodium:dicarboxylate symporter family signature 1. P.GElLMrMLKMLIlP |
| Chain | Residue | Details |
| A | PRO84-PRO98 | |
| site_id | PS00714 |
| Number of Residues | 24 |
| Details | NA_DICARBOXYL_SYMP_2 Sodium:dicarboxylate symporter family signature 2. PvGaTiNMDGTaLYeaVaaIFIAQ |
| Chain | Residue | Details |
| A | PRO372-GLN395 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"28424515","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"28424515","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"29872227","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 33 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"29872227","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"29872227","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 27 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"29872227","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"29872227","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 63 |
| Details | Intramembrane: {"description":"Discontinuously helical","evidences":[{"source":"PubMed","id":"29872227","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 26 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"29872227","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI11 |
| Number of Residues | 24 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI12 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"29872227","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI13 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28424515","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5LM4","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O59010","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI15 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P43003","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI16 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI17 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
