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5LLQ

Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119F variant

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0003908molecular_functionmethylated-DNA-[protein]-cysteine S-methyltransferase activity
A0005737cellular_componentcytoplasm
A0006281biological_processDNA repair
A0006307biological_processDNA alkylation repair
A0006974biological_processDNA damage response
A0008168molecular_functionmethyltransferase activity
A0016740molecular_functiontransferase activity
A0032259biological_processmethylation
B0003824molecular_functioncatalytic activity
B0003908molecular_functionmethylated-DNA-[protein]-cysteine S-methyltransferase activity
B0005737cellular_componentcytoplasm
B0006281biological_processDNA repair
B0006307biological_processDNA alkylation repair
B0006974biological_processDNA damage response
B0008168molecular_functionmethyltransferase activity
B0016740molecular_functiontransferase activity
B0032259biological_processmethylation
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue GOL B 201
ChainResidue
BLYS67
BTHR68
BARG72
BLYS110
BGOL202

site_idAC2
Number of Residues4
Detailsbinding site for residue GOL B 202
ChainResidue
BASN111
BPRO112
BARG133
BGOL201

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsActive site: {"description":"Nucleophile; methyl group acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00772","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

249697

PDB entries from 2026-02-25

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