5LKB
Crystal structure of the Xi glutathione transferase ECM4 from Saccharomyces cerevisiae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0045174 | molecular_function | glutathione dehydrogenase (ascorbate) activity |
| A | 0071555 | biological_process | cell wall organization |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0045174 | molecular_function | glutathione dehydrogenase (ascorbate) activity |
| B | 0071555 | biological_process | cell wall organization |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | LEU74 |
| A | HOH764 |
| A | ARG155 |
| A | TYR224 |
| A | HIS345 |
| A | HIS350 |
| A | HOH601 |
| A | HOH630 |
| A | HOH673 |
| A | HOH720 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | SER18 |
| A | TRP48 |
| A | VAL158 |
| A | PRO159 |
| A | ASN172 |
| A | GLU173 |
| A | SER174 |
| A | HOH535 |
| A | HOH662 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| B | ASN121 |
| B | ARG348 |
| B | THR351 |
| B | PRO355 |
| B | GLY357 |
| B | HOH585 |
| B | HOH652 |
| B | HOH705 |
| B | HOH740 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 304 |
| Details | Domain: {"description":"GST C-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"16709151","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27736955","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27736955","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5LKD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
