Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| C | 0020037 | molecular_function | heme binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| D | 0020037 | molecular_function | heme binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | LEU123 |
| A | GLY328 |
| A | VAL329 |
| A | ARG331 |
| A | VAL382 |
| A | PHE383 |
| A | HIS388 |
| A | CYS390 |
| A | GOL502 |
| A | HOH648 |
| A | ALA124 |
| A | HIS131 |
| A | ARG135 |
| A | GLY279 |
| A | GLY280 |
| A | THR283 |
| A | THR284 |
| A | SER325 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | GLY279 |
| A | HEM501 |
| A | GOL506 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ARG95 |
| A | LYS96 |
| A | SER97 |
| A | HOH602 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | ALA56 |
| A | ASN57 |
| C | HOH668 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 505 |
| Chain | Residue |
| A | HIS298 |
| A | PRO299 |
| A | ASP300 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 506 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 507 |
| Chain | Residue |
| A | PHE389 |
| A | ARG397 |
| A | HOH627 |
| A | HOH632 |
| D | PRO376 |
| D | LEU377 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 508 |
| Chain | Residue |
| A | ARG171 |
| A | LEU442 |
| A | LEU443 |
| A | HIS444 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue MES A 509 |
| Chain | Residue |
| A | ARG104 |
| A | ASP105 |
| A | SO4510 |
| A | SO4510 |
| D | PRO365 |
| D | SER366 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 510 |
| Chain | Residue |
| A | MES509 |
| A | MES509 |
| A | HOH641 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 511 |
| Chain | Residue |
| A | ALA167 |
| A | ARG410 |
| A | HIS444 |
| site_id | AD3 |
| Number of Residues | 22 |
| Details | binding site for residue HEM B 501 |
| Chain | Residue |
| B | LEU123 |
| B | ALA124 |
| B | HIS131 |
| B | ARG135 |
| B | PHE142 |
| B | LEU276 |
| B | GLY279 |
| B | GLY280 |
| B | THR283 |
| B | THR284 |
| B | LEU287 |
| B | GLY328 |
| B | VAL329 |
| B | ARG331 |
| B | VAL382 |
| B | PHE383 |
| B | GLY384 |
| B | HIS388 |
| B | CYS390 |
| B | VAL391 |
| B | HOH602 |
| B | HOH603 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| B | PRO376 |
| B | LEU377 |
| C | PHE389 |
| C | ARG397 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 503 |
| Chain | Residue |
| B | ARG74 |
| B | ARG95 |
| B | LYS96 |
| B | HOH630 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| B | ALA379 |
| B | ALA380 |
| B | ARG397 |
| C | LEU377 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 505 |
| Chain | Residue |
| B | ARG104 |
| C | SER366 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 506 |
| Chain | Residue |
| B | HIS298 |
| B | PRO299 |
| B | ASP300 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 507 |
| Chain | Residue |
| B | ARG112 |
| B | GLN115 |
| B | GLN127 |
| site_id | AE1 |
| Number of Residues | 22 |
| Details | binding site for residue HEM C 501 |
| Chain | Residue |
| C | GLY279 |
| C | GLY280 |
| C | THR283 |
| C | LEU287 |
| C | GLY328 |
| C | VAL329 |
| C | ARG331 |
| C | VAL382 |
| C | PHE383 |
| C | GLY385 |
| C | HIS388 |
| C | CYS390 |
| C | VAL391 |
| C | GLY392 |
| C | ALA396 |
| C | GOL505 |
| C | GOL506 |
| C | HOH606 |
| C | HOH681 |
| C | ALA124 |
| C | HIS131 |
| C | ARG135 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 502 |
| Chain | Residue |
| C | ARG112 |
| C | GLN115 |
| C | GLN127 |
| C | HOH636 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 503 |
| Chain | Residue |
| C | PRO81 |
| C | ARG95 |
| C | ASP341 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 504 |
| Chain | Residue |
| B | THR362 |
| C | ARG74 |
| C | ARG95 |
| C | LYS96 |
| C | SER97 |
| C | HOH604 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 505 |
| Chain | Residue |
| C | LEU119 |
| C | HEM501 |
| C | GOL506 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 506 |
| Chain | Residue |
| C | LEU278 |
| C | GLY279 |
| C | THR283 |
| C | HEM501 |
| C | GOL505 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS C 507 |
| Chain | Residue |
| C | HIS298 |
| C | PRO299 |
| C | ASP300 |
| site_id | AE8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 508 |
| Chain | Residue |
| B | ARG304 |
| C | ARG136 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 509 |
| Chain | Residue |
| C | ARG410 |
| C | HIS445 |
| site_id | AF1 |
| Number of Residues | 20 |
| Details | binding site for residue HEM D 501 |
| Chain | Residue |
| D | LEU123 |
| D | ALA124 |
| D | HIS131 |
| D | ARG135 |
| D | LEU276 |
| D | GLY279 |
| D | GLY280 |
| D | THR283 |
| D | LEU287 |
| D | VAL329 |
| D | ARG331 |
| D | VAL382 |
| D | PHE383 |
| D | GLY384 |
| D | HIS388 |
| D | CYS390 |
| D | VAL391 |
| D | GOL502 |
| D | GOL505 |
| D | HOH627 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL D 502 |
| Chain | Residue |
| D | ALA124 |
| D | HEM501 |
| D | GOL505 |
| site_id | AF3 |
| Number of Residues | 2 |
| Details | binding site for residue DMS D 503 |
| Chain | Residue |
| D | ARG304 |
| D | DMS506 |
| site_id | AF4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS D 504 |
| Chain | Residue |
| D | ARG74 |
| D | ARG95 |
| D | LYS96 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 505 |
| Chain | Residue |
| D | GLY279 |
| D | THR283 |
| D | HEM501 |
| D | GOL502 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue DMS D 506 |
| Chain | Residue |
| A | ARG136 |
| D | DMS503 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 507 |
| Chain | Residue |
| A | THR100 |
| A | ARG104 |
| A | GLY386 |
| D | ARG374 |
| D | LYS375 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 508 |
| Chain | Residue |
| D | ALA167 |
| D | ARG410 |
| D | HIS444 |
| site_id | AF9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 509 |
| Chain | Residue |
| D | ARG112 |
| D | GLN115 |
| D | GLN127 |
| site_id | AG1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 510 |
| Chain | Residue |
| A | LEU377 |
| D | PHE389 |
| D | ARG397 |
| site_id | AG2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 511 |
| Chain | Residue |
| C | ARG112 |
| D | PRO54 |
| D | LEU55 |
| site_id | AG3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 512 |
| Chain | Residue |
| D | LEU442 |
| D | LEU443 |
| D | HIS444 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGgGAHFCVG |
| Chain | Residue | Details |
| A | PHE383-GLY392 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS390 | |
| B | CYS390 | |
| C | CYS390 | |
| D | CYS390 | |
