Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004407 | molecular_function | histone deacetylase activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0040029 | biological_process | epigenetic regulation of gene expression |
A | 0046872 | molecular_function | metal ion binding |
B | 0004407 | molecular_function | histone deacetylase activity |
B | 0016787 | molecular_function | hydrolase activity |
B | 0040029 | biological_process | epigenetic regulation of gene expression |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 401 |
Chain | Residue |
A | ASP181 |
A | HIS183 |
A | ASP269 |
A | 9RB404 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue K A 402 |
Chain | Residue |
A | ASP179 |
A | ASP181 |
A | HIS183 |
A | SER202 |
A | LEU203 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue K A 403 |
Chain | Residue |
A | TYR192 |
A | ARG195 |
A | VAL198 |
A | SER200 |
A | PHE227 |
A | HOH503 |
A | HOH527 |
site_id | AC4 |
Number of Residues | 14 |
Details | binding site for residue 9RB A 404 |
Chain | Residue |
A | THR24 |
A | ASP101 |
A | HIS143 |
A | HIS144 |
A | PHE153 |
A | ASP181 |
A | HIS183 |
A | PHE209 |
A | ASP269 |
A | TYR313 |
A | ZN401 |
A | HOH510 |
B | LEU340 |
B | PHE343 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue ZN B 401 |
Chain | Residue |
B | ASP181 |
B | HIS183 |
B | ASP269 |
B | 9RB404 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue K B 402 |
Chain | Residue |
B | ASP179 |
B | ASP181 |
B | HIS183 |
B | SER202 |
B | LEU203 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue K B 403 |
Chain | Residue |
B | TYR192 |
B | ARG195 |
B | VAL198 |
B | PHE227 |
B | HOH538 |
B | HOH553 |
site_id | AC8 |
Number of Residues | 14 |
Details | binding site for residue 9RB B 404 |
Chain | Residue |
A | LEU340 |
A | PHE343 |
B | THR24 |
B | ASP101 |
B | HIS143 |
B | HIS144 |
B | PHE153 |
B | ASP181 |
B | HIS183 |
B | PHE209 |
B | ASP269 |
B | TYR313 |
B | ZN401 |
B | HOH502 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS144 | |
B | HIS144 | |
Chain | Residue | Details |
A | ASP181 | |
A | HIS183 | |
A | ASP269 | |
B | ASP181 | |
B | HIS183 | |
B | ASP269 | |
Chain | Residue | Details |
A | TYR313 | |
B | TYR313 | |