Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004175 | molecular_function | endopeptidase activity |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0006508 | biological_process | proteolysis |
A | 0007586 | biological_process | digestion |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0097180 | cellular_component | serine protease inhibitor complex |
A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue DMS A 301 |
Chain | Residue |
A | VAL76 |
A | SER96 |
A | ASN97 |
A | HOH429 |
A | HOH437 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue DMS A 302 |
Chain | Residue |
A | VAL90 |
A | HIS91 |
A | TYR94 |
A | HOH411 |
A | ARG66 |
A | ILE73 |
A | ASN74 |
A | PHE82 |
site_id | AC3 |
Number of Residues | 6 |
Details | binding site for residue CA A 303 |
Chain | Residue |
A | GLU70 |
A | ASN72 |
A | VAL75 |
A | GLU80 |
A | HOH408 |
A | HOH411 |
site_id | AC4 |
Number of Residues | 24 |
Details | binding site for residue 6WH A 304 |
Chain | Residue |
A | PHE41 |
A | HIS57 |
A | LYS87 |
A | LEU99 |
A | TYR151 |
A | ASP189 |
A | SER190 |
A | CYS191 |
A | GLN192 |
A | GLY193 |
A | ASP194 |
A | SER195 |
A | VAL213 |
A | TRP215 |
A | GLY216 |
A | GLY219 |
A | GLY226 |
A | SER244 |
A | HOH431 |
A | HOH533 |
A | HOH578 |
A | HOH596 |
A | HOH598 |
A | HOH600 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
Chain | Residue | Details |
A | VAL53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
Chain | Residue | Details |
A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 7 |
Details | BINDING: |
Chain | Residue | Details |
A | GLU70 | |
A | ASN72 | |
A | VAL75 | |
A | GLU80 | |
A | ASP189 | |
A | GLN192 | |
A | SER195 | |