5LFO

Crystal structure of murine N1-acetylpolyamine oxidase in complex with N1-acetylspermine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	41
Details	binding site for residue FAD A 1801

Chain	Residue
A	VAL11
A	GLY43
A	GLY44
A	ARG45
A	GLY59
A	ALA60
A	HIS61
A	TRP62
A	HIS64
A	PRO239
A	VAL240
A	GLY12
A	THR279
A	VAL280
A	PRO281
A	PHE284
A	ASN313
A	TRP420
A	TYR425
A	TYR430
A	GLY464
A	GLU465
A	GLY14
A	SER473
A	THR474
A	THR475
A	ALA478
A	SP51802
A	HOH1937
A	HOH1958
A	HOH1969
A	HOH1976
A	HOH1984
A	ILE15
A	HOH1986
A	HOH2051
A	ALA16
A	LEU36
A	GLU37
A	ALA38
A	THR39

---

site_id	AC2
Number of Residues	15
Details	binding site for residue SP5 A 1802

Chain	Residue
A	TRP62
A	HIS64
A	CYS186
A	VAL187
A	PHE201
A	TYR204
A	ASN313
A	PHE375
A	TYR430
A	SER473
A	FAD1801
A	HOH1904
A	HOH1993
A	HOH2037
A	HOH2038

---

site_id	AC3
Number of Residues	8
Details	binding site for residue GOL A 1803

Chain	Residue
A	GLY268
A	PHE310
A	LEU347
A	HOH1927
A	HOH1990
A	HOH2043
A	HOH2109
A	HOH2114

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:28029774, ECO:0007744|PDB:5LAE, ECO:0007744|PDB:5LFO, ECO:0007744|PDB:5MBX

Chain	Residue	Details
A	ALA16
A	GLU37
A	ARG45
A	HIS61
A	VAL240
A	GLU465
A	THR474

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:28029774, ECO:0007744|PDB:5MBX

Chain	Residue	Details
A	HIS64

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:28029774, ECO:0007744|PDB:5LFO, ECO:0007744|PDB:5MBX

Chain	Residue	Details
A	VAL187
A	ASN313

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