5LFG

X-ray structure of a new fully ligated carbomonoxy form of Trematomus newnesi hemoglobin (Hb1TnCO).

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005344	molecular_function	oxygen carrier activity
A	0005506	molecular_function	iron ion binding
A	0005833	cellular_component	hemoglobin complex
A	0015671	biological_process	oxygen transport
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0031720	molecular_function	haptoglobin binding
A	0031838	cellular_component	haptoglobin-hemoglobin complex
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0043177	molecular_function	organic acid binding
A	0046872	molecular_function	metal ion binding
A	0072562	cellular_component	blood microparticle
A	0098869	biological_process	cellular oxidant detoxification
B	0004601	molecular_function	peroxidase activity
B	0005344	molecular_function	oxygen carrier activity
B	0005833	cellular_component	hemoglobin complex
B	0015671	biological_process	oxygen transport
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
B	0031720	molecular_function	haptoglobin binding
B	0031838	cellular_component	haptoglobin-hemoglobin complex
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0043177	molecular_function	organic acid binding
B	0046872	molecular_function	metal ion binding
B	0072562	cellular_component	blood microparticle
B	0098869	biological_process	cellular oxidant detoxification
C	0004601	molecular_function	peroxidase activity
C	0005344	molecular_function	oxygen carrier activity
C	0005506	molecular_function	iron ion binding
C	0005833	cellular_component	hemoglobin complex
C	0015671	biological_process	oxygen transport
C	0019825	molecular_function	oxygen binding
C	0020037	molecular_function	heme binding
C	0031720	molecular_function	haptoglobin binding
C	0031838	cellular_component	haptoglobin-hemoglobin complex
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0043177	molecular_function	organic acid binding
C	0046872	molecular_function	metal ion binding
C	0072562	cellular_component	blood microparticle
C	0098869	biological_process	cellular oxidant detoxification
D	0004601	molecular_function	peroxidase activity
D	0005344	molecular_function	oxygen carrier activity
D	0005833	cellular_component	hemoglobin complex
D	0015671	biological_process	oxygen transport
D	0019825	molecular_function	oxygen binding
D	0020037	molecular_function	heme binding
D	0031720	molecular_function	haptoglobin binding
D	0031838	cellular_component	haptoglobin-hemoglobin complex
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0043177	molecular_function	organic acid binding
D	0046872	molecular_function	metal ion binding
D	0072562	cellular_component	blood microparticle
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CMO A 201

Chain	Residue
A	HIS59
A	VAL63
A	HEM202

---

site_id	AC2
Number of Residues	17
Details	binding site for residue HEM A 202

Chain	Residue
A	VAL63
A	LEU84
A	HIS88
A	LEU92
A	VAL94
A	ASN98
A	LEU102
A	ASN103
A	LEU137
A	CMO201
A	HOH316
A	TYR42
A	PHE43
A	HIS45
A	TRP46
A	HIS59
A	LYS62

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CMO B 201

Chain	Residue
B	HIS63
B	VAL67
B	HEM202

---

site_id	AC4
Number of Residues	13
Details	binding site for residue HEM B 202

Chain	Residue
B	TYR41
B	PHE45
B	HIS63
B	LYS66
B	VAL67
B	LEU91
B	HIS92
B	LEU96
B	VAL98
B	ASN102
B	PHE103
B	LEU141
B	CMO201

---

site_id	AC5
Number of Residues	3
Details	binding site for residue CMO C 201

Chain	Residue
C	HIS59
C	VAL63
C	HEM202

---

site_id	AC6
Number of Residues	18
Details	binding site for residue HEM C 202

Chain	Residue
B	ASN47
C	TYR42
C	HIS45
C	TRP46
C	HIS59
C	LYS62
C	VAL63
C	LEU84
C	GLN87
C	HIS88
C	LYS91
C	LEU92
C	VAL94
C	ASN98
C	PHE99
C	LEU102
C	LEU137
C	CMO201

---

site_id	AC7
Number of Residues	12
Details	binding site for residue HEM D 201

Chain	Residue
D	THR38
D	TYR41
D	PHE42
D	PHE45
D	HIS63
D	LEU88
D	HIS92
D	LEU96
D	ASN102
D	PHE103
D	LEU141
D	CMO202

---

site_id	AC8
Number of Residues	3
Details	binding site for residue CMO D 202

Chain	Residue
D	VAL67
D	HIS92
D	HEM201

---

site_id	AC9
Number of Residues	5
Details	binding site for Di-peptide ACE C 0 and SER C 1

Chain	Residue
C	LEU2
C	SER3
C	LYS128
C	GLU139
C	ARG142

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: distal binding residue => ECO:0000269|PubMed:12093902, ECO:0007744|PDB:1LA6

Chain	Residue	Details
B	HIS63
D	HIS63

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: proximal binding residue => ECO:0000269|PubMed:12093902, ECO:0007744|PDB:1LA6, ECO:0007744|PDB:1T1N, ECO:0007744|PDB:3D1K, ECO:0007744|PDB:3NFE, ECO:0007744|PDB:3NG6

Chain	Residue	Details
B	HIS92
D	HIS92

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N-acetylserine => ECO:0000269|PubMed:8144556

Chain	Residue	Details
A	SER1
C	SER1

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