5LDQ
Crystal structure of E.coli LigT complexed with NADP+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004113 | molecular_function | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0008664 | molecular_function | RNA 2',3'-cyclic 3'-phosphodiesterase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016874 | molecular_function | ligase activity |
| B | 0004113 | molecular_function | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0008664 | molecular_function | RNA 2',3'-cyclic 3'-phosphodiesterase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016874 | molecular_function | ligase activity |
| C | 0004113 | molecular_function | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| C | 0008664 | molecular_function | RNA 2',3'-cyclic 3'-phosphodiesterase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016874 | molecular_function | ligase activity |
| D | 0004113 | molecular_function | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| D | 0008664 | molecular_function | RNA 2',3'-cyclic 3'-phosphodiesterase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | binding site for residue NAP A 201 |
| Chain | Residue |
| A | ARG6 |
| A | PHE159 |
| A | THR164 |
| A | TYR166 |
| A | HOH308 |
| A | HOH316 |
| A | HOH321 |
| A | HOH397 |
| A | HOH407 |
| B | ARG84 |
| B | SER85 |
| A | HIS43 |
| B | ARG86 |
| B | ARG120 |
| B | ASP131 |
| B | NAP201 |
| B | HOH321 |
| B | HOH366 |
| B | HOH380 |
| A | THR45 |
| A | PHE48 |
| A | HIS125 |
| A | THR127 |
| A | ARG130 |
| A | SER157 |
| A | SER158 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue NAP A 202 |
| Chain | Residue |
| A | GLN81 |
| A | TRP82 |
| A | LEU83 |
| A | ARG84 |
| A | SER85 |
| A | ARG120 |
| A | HIS123 |
| B | GLU134 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 203 |
| Chain | Residue |
| A | ALA38 |
| A | ASN41 |
| A | HOH471 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue 1PE A 204 |
| Chain | Residue |
| A | TRP89 |
| A | MET92 |
| A | PRO95 |
| A | HIS123 |
| A | PRO124 |
| A | HOH327 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | binding site for residue NAP B 201 |
| Chain | Residue |
| A | PRO4 |
| A | GLU51 |
| A | NAP201 |
| A | HOH409 |
| B | ARG6 |
| B | PHE8 |
| B | HIS43 |
| B | THR45 |
| B | PHE48 |
| B | ASN119 |
| B | ARG120 |
| B | ARG130 |
| B | SER157 |
| B | THR164 |
| B | TYR166 |
| B | CL202 |
| B | HOH314 |
| B | HOH319 |
| B | HOH338 |
| B | HOH354 |
| B | HOH363 |
| B | HOH421 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 202 |
| Chain | Residue |
| B | ARG130 |
| B | NAP201 |
| B | HOH407 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue 1PE B 203 |
| Chain | Residue |
| A | ARG86 |
| B | GLN81 |
| B | TRP82 |
| B | LEU83 |
| B | ARG84 |
| B | SER85 |
| B | HOH309 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | binding site for residue NAP C 201 |
| Chain | Residue |
| C | ARG6 |
| C | PHE8 |
| C | HIS43 |
| C | THR45 |
| C | PHE48 |
| C | PHE116 |
| C | HIS125 |
| C | THR127 |
| C | ARG130 |
| C | SER157 |
| C | PHE159 |
| C | THR164 |
| C | TYR166 |
| C | HOH315 |
| C | HOH385 |
| D | ARG6 |
| D | GLY50 |
| D | GLU51 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL C 202 |
| Chain | Residue |
| C | ASN41 |
| C | ARG165 |
| C | TYR166 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residue 1PE C 203 |
| Chain | Residue |
| A | HOH406 |
| C | PRO14 |
| C | ALA15 |
| C | GLU16 |
| C | ARG18 |
| C | ASP40 |
| C | HOH353 |
| C | HOH380 |
| A | PHE143 |
| A | ASN144 |
| A | HOH376 |
| site_id | AD2 |
| Number of Residues | 19 |
| Details | binding site for residue NAP D 201 |
| Chain | Residue |
| C | ARG84 |
| C | ARG86 |
| C | ASP131 |
| C | HOH307 |
| D | ARG6 |
| D | PHE8 |
| D | HIS43 |
| D | THR45 |
| D | PHE48 |
| D | HIS125 |
| D | THR127 |
| D | ARG130 |
| D | SER157 |
| D | TYR166 |
| D | HOH302 |
| D | HOH326 |
| D | HOH330 |
| D | HOH366 |
| D | HOH378 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 D 202 |
| Chain | Residue |
| C | ARG84 |
| D | VAL37 |
| D | ALA38 |
| D | ASN41 |
| D | ARG130 |
| D | HOH305 |
| D | HOH307 |
