5LBN
High-resolution crystal structure of the UBC core domain of UBE2E1/UbcH6
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 201 |
| Chain | Residue |
| A | THR47 |
| A | LYS50 |
| A | SER68 |
| A | ARG80 |
| A | SER81 |
| A | THR82 |
| A | HOH320 |
| A | HOH329 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | LYS112 |
| A | VAL113 |
| A | THR114 |
| A | VAL129 |
| A | ILE130 |
| A | LEU135 |
| A | HOH327 |
| A | PRO111 |
Functional Information from PROSITE/UniProt
| site_id | PS00183 |
| Number of Residues | 16 |
| Details | UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHCNInsq.GvICLdiL |
| Chain | Residue | Details |
| A | TYR120-LEU135 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 146 |
| Details | Domain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10133","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15)"} |
| Chain | Residue | Details |
