5LBN

High-resolution crystal structure of the UBC core domain of UBE2E1/UbcH6

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue GOL A 201

Chain	Residue
A	THR47
A	LYS50
A	SER68
A	ARG80
A	SER81
A	THR82
A	HOH320
A	HOH329

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site_id	AC2
Number of Residues	8
Details	binding site for residue GOL A 202

Chain	Residue
A	LYS112
A	VAL113
A	THR114
A	VAL129
A	ILE130
A	LEU135
A	HOH327
A	PRO111

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Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	16
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHCNInsq.GvICLdiL

Chain	Residue	Details
A	TYR120-LEU135

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133

Chain	Residue	Details
A	CYS131

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15)

Chain	Residue	Details
A	LYS136

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