5LAA

X-RAY STRUCTURE OF THE METHYLTRANSFERASE SUBUNIT A FROM METHANOTHERMUS FERVIDUS IN COMPLEX WITH COBALAMIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006730	biological_process	one-carbon metabolic process
A	0006814	biological_process	sodium ion transport
A	0008168	molecular_function	methyltransferase activity
A	0015948	biological_process	methanogenesis
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0019386	biological_process	methanogenesis, from carbon dioxide
A	0030269	molecular_function	tetrahydromethanopterin S-methyltransferase activity
A	0032259	biological_process	methylation
A	0035725	biological_process	sodium ion transmembrane transport
A	0050897	molecular_function	cobalt ion binding
B	0005886	cellular_component	plasma membrane
B	0006730	biological_process	one-carbon metabolic process
B	0006814	biological_process	sodium ion transport
B	0008168	molecular_function	methyltransferase activity
B	0015948	biological_process	methanogenesis
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0019386	biological_process	methanogenesis, from carbon dioxide
B	0030269	molecular_function	tetrahydromethanopterin S-methyltransferase activity
B	0032259	biological_process	methylation
B	0035725	biological_process	sodium ion transmembrane transport
B	0050897	molecular_function	cobalt ion binding
C	0005886	cellular_component	plasma membrane
C	0006730	biological_process	one-carbon metabolic process
C	0006814	biological_process	sodium ion transport
C	0008168	molecular_function	methyltransferase activity
C	0015948	biological_process	methanogenesis
C	0016020	cellular_component	membrane
C	0016740	molecular_function	transferase activity
C	0019386	biological_process	methanogenesis, from carbon dioxide
C	0030269	molecular_function	tetrahydromethanopterin S-methyltransferase activity
C	0032259	biological_process	methylation
C	0035725	biological_process	sodium ion transmembrane transport
C	0050897	molecular_function	cobalt ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue B12 A 201

Chain	Residue
A	GLY16
A	CYS51
A	LYS52
A	THR53
A	ASN55
A	GLY57
A	LYS60
A	ASN64
A	GLN82
A	HIS84
A	ALA110
A	ASP17
A	ILE111
B	HIS35
B	GLU37
A	TYR18
A	ALA29
A	VAL30
A	ALA33
A	ILE47
A	GLY49
A	PRO50

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site_id	AC2
Number of Residues	24
Details	binding site for residue B12 B 201

Chain	Residue
B	GLY16
B	ASP17
B	TYR18
B	ALA29
B	VAL30
B	ALA33
B	GLY49
B	PRO50
B	CYS51
B	LYS52
B	THR53
B	GLU54
B	ASN55
B	GLY57
B	LYS60
B	VAL61
B	ASN64
B	GLN82
B	HIS84
B	ALA110
B	ILE111
C	HIS35
C	ILE36
C	GLU37

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site_id	AC3
Number of Residues	22
Details	binding site for residue B12 C 201

Chain	Residue
A	HIS35
A	GLU37
C	GLY16
C	ASP17
C	TYR18
C	ALA29
C	VAL30
C	ALA33
C	ILE47
C	GLY49
C	PRO50
C	LYS52
C	THR53
C	ASN55
C	GLY57
C	LYS60
C	ASN64
C	GLN82
C	GLY83
C	HIS84
C	ALA110
C	ILE111

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