5L8N
crystal structure of human FABP6 protein with fragment 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005319 | molecular_function | lipid transporter activity |
| A | 0005504 | molecular_function | fatty acid binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006869 | biological_process | lipid transport |
| A | 0008285 | biological_process | negative regulation of cell population proliferation |
| A | 0008289 | molecular_function | lipid binding |
| A | 0015908 | biological_process | fatty acid transport |
| A | 0016020 | cellular_component | membrane |
| A | 0019433 | biological_process | triglyceride catabolic process |
| B | 0005319 | molecular_function | lipid transporter activity |
| B | 0005504 | molecular_function | fatty acid binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006869 | biological_process | lipid transport |
| B | 0008285 | biological_process | negative regulation of cell population proliferation |
| B | 0008289 | molecular_function | lipid binding |
| B | 0015908 | biological_process | fatty acid transport |
| B | 0016020 | cellular_component | membrane |
| B | 0019433 | biological_process | triglyceride catabolic process |
| C | 0005319 | molecular_function | lipid transporter activity |
| C | 0005504 | molecular_function | fatty acid binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0006869 | biological_process | lipid transport |
| C | 0008285 | biological_process | negative regulation of cell population proliferation |
| C | 0008289 | molecular_function | lipid binding |
| C | 0015908 | biological_process | fatty acid transport |
| C | 0016020 | cellular_component | membrane |
| C | 0019433 | biological_process | triglyceride catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue 6RQ A 1001 |
| Chain | Residue |
| A | GLU12 |
| A | TYR15 |
| A | ALA32 |
| A | ARG33 |
| A | ILE37 |
| A | MET75 |
| A | ARG122 |
| B | LYS63 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 1002 |
| Chain | Residue |
| A | SER102 |
| A | GLN100 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 2001 |
| Chain | Residue |
| B | LEU22 |
| B | LYS78 |
| B | PHE95 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue PEG B 2002 |
| Chain | Residue |
| B | ALA2 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue P33 B 2003 |
| Chain | Residue |
| B | PHE18 |
| B | TRP50 |
| B | ILE72 |
| B | THR74 |
| B | GLY76 |
| B | LEU91 |
| B | TYR98 |
| B | GLN100 |
| B | THR101 |
| B | SER102 |
| B | ARG122 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue 6RQ C 1001 |
| Chain | Residue |
| C | MET9 |
| C | GLU12 |
| C | TYR15 |
| C | ALA32 |
| C | ARG33 |
| C | ILE37 |
| C | TYR54 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue PEG C 1002 |
| Chain | Residue |
| C | TRP50 |
| C | GLN52 |
| C | GLN100 |
| C | SER102 |
Functional Information from PROSITE/UniProt
| site_id | PS00214 |
| Number of Residues | 18 |
| Details | FABP Cytosolic fatty-acid binding proteins signature. GKFeMesEkNYDeFMKLL |
| Chain | Residue | Details |
| A | GLY5-LEU22 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"P10289","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
