Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS218 |
| A | HIS222 |
| A | HIS228 |
| A | R47306 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 302 |
| Chain | Residue |
| A | HIS168 |
| A | ASP170 |
| A | HIS183 |
| A | HIS196 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 303 |
| Chain | Residue |
| A | GLY176 |
| A | GLY178 |
| A | ILE180 |
| A | ASP198 |
| A | GLU201 |
| A | ASP175 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 304 |
| Chain | Residue |
| A | ASP158 |
| A | GLY190 |
| A | GLY192 |
| A | ASP194 |
| A | HOH409 |
| A | HOH424 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 305 |
| Chain | Residue |
| A | ASP124 |
| A | GLU199 |
| A | GLU201 |
| A | HOH458 |
| A | HOH467 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | ASP124 |
| A | GLY188 |
| A | SER189 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | GLY186 |
| A | PRO187 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | TYR113 |
| A | VAL144 |
| A | PRO146 |
| A | GLY166 |
| A | ALA167 |
| A | HOH407 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | ALA157 |
| A | GLY190 |
| A | 6PJ307 |
| A | HOH404 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 312 |
| Chain | Residue |
| A | HIS168 |
| A | ARG249 |
| A | LEU250 |
| A | ILE255 |
| A | 6PJ307 |
| A | HOH402 |
| site_id | AD2 |
| Number of Residues | 41 |
| Details | binding site for residues R47 A 306 and 6PJ A 307 |
| Chain | Residue |
| A | ARG127 |
| A | THR154 |
| A | GLY178 |
| A | GLY179 |
| A | LEU181 |
| A | ALA182 |
| A | HIS183 |
| A | GLY190 |
| A | THR215 |
| A | HIS218 |
| A | GLU219 |
| A | HIS222 |
| A | HIS228 |
| A | PRO232 |
| A | PRO232 |
| A | LYS233 |
| A | ALA234 |
| A | VAL235 |
| A | PHE237 |
| A | PRO238 |
| A | THR239 |
| A | TYR240 |
| A | LYS241 |
| A | VAL243 |
| A | PHE248 |
| A | ARG249 |
| A | LEU250 |
| A | SER251 |
| A | ALA252 |
| A | ZN301 |
| A | EDO311 |
| A | GOL312 |
| A | HOH401 |
| A | HOH402 |
| A | HOH410 |
| A | HOH412 |
| A | HOH423 |
| A | HOH424 |
| A | HOH427 |
| A | HOH435 |
| A | HOH446 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TAVHEIGHSL |
| Chain | Residue | Details |
| A | THR215-LEU224 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 19 |
| Details | Binding site: {} |
