5L76
Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain (in apo form)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1001 |
| Chain | Residue |
| A | GLU798 |
| A | TRP799 |
| A | GLY801 |
| A | HOH1111 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 1002 |
| Chain | Residue |
| A | THR920 |
| A | SER922 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 1003 |
| Chain | Residue |
| A | GLU600 |
| A | TYR708 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1004 |
| Chain | Residue |
| A | GLY679 |
| A | PHE682 |
| A | LEU683 |
| A | MET731 |
| A | ASN735 |
| A | VAL661 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1005 |
| Chain | Residue |
| A | ASP857 |
| A | VAL859 |
| A | ILE917 |
| A | TYR918 |
| A | THR919 |
| A | HOH1132 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 1006 |
| Chain | Residue |
| A | TYR632 |
| A | TYR667 |
| A | ALA685 |
| A | THR687 |
| A | GLY699 |
| A | HOH1131 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2016","submissionDatabase":"PDB data bank","title":"Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain (in NAD+ bound form).","authors":["Kopec J.","Yue W.W."]}},{"source":"PDB","id":"5L78","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9P4R4","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q99K67","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q99K67","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q99K67","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
