5L76

Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain (in apo form)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue EDO A 1001

Chain	Residue
A	GLU798
A	TRP799
A	GLY801
A	HOH1111

---

site_id	AC2
Number of Residues	2
Details	binding site for residue EDO A 1002

Chain	Residue
A	THR920
A	SER922

---

site_id	AC3
Number of Residues	2
Details	binding site for residue EDO A 1003

Chain	Residue
A	GLU600
A	TYR708

---

site_id	AC4
Number of Residues	6
Details	binding site for residue EDO A 1004

Chain	Residue
A	GLY679
A	PHE682
A	LEU683
A	MET731
A	ASN735
A	VAL661

---

site_id	AC5
Number of Residues	6
Details	binding site for residue EDO A 1005

Chain	Residue
A	ASP857
A	VAL859
A	ILE917
A	TYR918
A	THR919
A	HOH1132

---

site_id	AC6
Number of Residues	6
Details	binding site for residue PEG A 1006

Chain	Residue
A	TYR632
A	TYR667
A	ALA685
A	THR687
A	GLY699
A	HOH1131

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|Ref.8, ECO:0007744|PDB:5L78

Chain	Residue	Details
A	SER488
A	PRO605
A	ASP512
A	GLN516
A	ILE533
A	LEU554
A	ALA576
A	SER577
A	LEU603
A	ASP604

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9P4R4

Chain	Residue	Details
A	ARG703
A	THR724

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q99K67

Chain	Residue	Details
A	LYS458
A	LYS523
A	LYS535
A	LYS584
A	LYS761

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q99K67

Chain	Residue	Details
A	LYS707
A	LYS739
A	LYS780

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q99K67

Chain	Residue	Details
A	LYS732

---