5L0V
human POGLUT1 in complex with 2F-glucose modified EGF(+) and UDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005788 | cellular_component | endoplasmic reticulum lumen |
| A | 0006486 | biological_process | obsolete protein glycosylation |
| A | 0006493 | biological_process | protein O-linked glycosylation |
| A | 0007369 | biological_process | gastrulation |
| A | 0010470 | biological_process | regulation of gastrulation |
| A | 0012505 | cellular_component | endomembrane system |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0035251 | molecular_function | UDP-glucosyltransferase activity |
| A | 0035252 | molecular_function | UDP-xylosyltransferase activity |
| A | 0045747 | biological_process | positive regulation of Notch signaling pathway |
| A | 0046527 | molecular_function | glucosyltransferase activity |
| A | 0060537 | biological_process | muscle tissue development |
| A | 0140561 | molecular_function | EGF-domain serine glucosyltransferase activity |
| A | 0140562 | molecular_function | EGF-domain serine xylosyltransferase activity |
| A | 0180059 | biological_process | protein O-linked glycosylation via glucose |
| A | 0180064 | biological_process | protein O-linked glycosylation via xylose |
| B | 0005509 | molecular_function | calcium ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS00010 |
| Number of Residues | 12 |
| Details | ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CvNtvgsYtClC |
| Chain | Residue | Details |
| B | CYS16-CYS27 |
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. ClCppGftGPnC |
| Chain | Residue | Details |
| B | CYS25-CYS36 |
| site_id | PS01186 |
| Number of Residues | 12 |
| Details | EGF_2 EGF-like domain signature 2. ClCppGFtgpn....C |
| Chain | Residue | Details |
| B | CYS25-CYS36 |
| site_id | PS01187 |
| Number of Residues | 25 |
| Details | EGF_CA Calcium-binding EGF-like domain signature. DiDECasnp..........Cqnggt..CvNtvgsYtC |
| Chain | Residue | Details |
| B | ASP1-CYS25 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Region: {"description":"Interaction with the consensus sequence C-X-S-X-[PA]-C in peptide substrates","evidences":[{"source":"PubMed","id":"28775322","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"28775322","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28775322","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5L0U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction with the consensus sequence C-X-S-X-[PA]-C in peptide substrates","evidences":[{"source":"PubMed","id":"28775322","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"28775322","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5L0V","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
