5L0S
human POGLUT1 in complex with Factor VII EGF1 and UDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001756 | biological_process | somitogenesis |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005788 | cellular_component | endoplasmic reticulum lumen |
| A | 0006486 | biological_process | protein glycosylation |
| A | 0006493 | biological_process | protein O-linked glycosylation |
| A | 0007369 | biological_process | gastrulation |
| A | 0008593 | biological_process | regulation of Notch signaling pathway |
| A | 0010470 | biological_process | regulation of gastrulation |
| A | 0012505 | cellular_component | endomembrane system |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0018242 | biological_process | protein O-linked glycosylation via serine |
| A | 0035251 | molecular_function | UDP-glucosyltransferase activity |
| A | 0035252 | molecular_function | UDP-xylosyltransferase activity |
| A | 0045747 | biological_process | positive regulation of Notch signaling pathway |
| A | 0046527 | molecular_function | glucosyltransferase activity |
| A | 0048318 | biological_process | axial mesoderm development |
| A | 0048339 | biological_process | paraxial mesoderm development |
| A | 0060537 | biological_process | muscle tissue development |
| A | 0072359 | biological_process | circulatory system development |
| A | 0140561 | molecular_function | EGF-domain serine glucosyltransferase activity |
| A | 0140562 | molecular_function | EGF-domain serine xylosyltransferase activity |
| B | 0005509 | molecular_function | calcium ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS00010 |
| Number of Residues | 12 |
| Details | ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CkDqlqsYiCfC |
| Chain | Residue | Details |
| B | CYS61-CYS72 |
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CfClpAfeGRnC |
| Chain | Residue | Details |
| B | CYS70-CYS81 |
| site_id | PS01187 |
| Number of Residues | 25 |
| Details | EGF_CA Calcium-binding EGF-like domain signature. DgDQCassp..........Cqnggs..CkDqlqsYiC |
| Chain | Residue | Details |
| B | ASP46-CYS70 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Important for S-112 for O-xylosylation |
| Chain | Residue | Details |
| B | SER53 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: (3R)-3-hydroxyaspartate => ECO:0000269|PubMed:3264725 |
| Chain | Residue | Details |
| B | ASP63 | |
| A | SER212 | |
| A | ARG218 | |
| A | VAL274 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: O-linked (Xyl...) serine; alternate => ECO:0000269|PubMed:1904059, ECO:0000269|PubMed:2129367, ECO:0000269|PubMed:21949356, ECO:0000269|PubMed:2511201 |
| Chain | Residue | Details |
| B | SER52 | |
| A | GLN240 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: O-linked (Fuc) serine => ECO:0000269|PubMed:1904059, ECO:0000269|PubMed:9023546 |
| Chain | Residue | Details |
| B | SER60 | |
| A | ASN53 | |
| A | ASN204 | |
| A | ASN373 |
