Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0004518 | molecular_function | nuclease activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | binding site for residue THP A 201 |
Chain | Residue |
A | ARG35 |
A | HOH308 |
A | HOH309 |
A | HOH313 |
A | HOH314 |
A | HOH322 |
A | HOH331 |
A | HOH340 |
A | HOH341 |
A | HOH356 |
A | HOH361 |
A | ASP40 |
A | HOH382 |
A | HOH386 |
A | HOH392 |
A | LYS84 |
A | TYR85 |
A | ARG87 |
A | TYR113 |
A | TYR115 |
A | LYS127 |
A | CA202 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue CA A 202 |
Chain | Residue |
A | ASP21 |
A | ASP40 |
A | THR41 |
A | GLU43 |
A | THP201 |
A | HOH313 |
A | HOH370 |
Functional Information from PROSITE/UniProt
site_id | PS01123 |
Number of Residues | 25 |
Details | TNASE_1 Thermonuclease family signature 1. DGDTVkLmykgqpmtf.RLllVDtPE |
Chain | Residue | Details |
A | ASP19-GLU43 | |
site_id | PS01284 |
Number of Residues | 11 |
Details | TNASE_2 Thermonuclease family signature 2. DKYGRgLAyIY |
Chain | Residue | Details |
A | ASP83-TYR93 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 16 |
Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | Active site: {"evidences":[{"source":"PubMed","id":"288045","evidenceCode":"ECO:0000269"}]} |
site_id | SWS_FT_FI3 |
Number of Residues | 3 |
Details | Binding site: {} |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 6 |
Details | M-CSA 165 |
Chain | Residue | Details |
A | ASP21 | metal ligand |
A | ARG35 | electrostatic stabiliser, hydrogen bond donor |
A | ASP40 | metal ligand |
A | THR41 | metal ligand |
A | GLU43 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | ARG87 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |