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5KWJ

M.tb Ag85C modified at C209 by amino-ebselen

Functional Information from GO Data
ChainGOidnamespacecontents
A0004144molecular_functiondiacylglycerol O-acyltransferase activity
A0005576cellular_componentextracellular region
A0006869biological_processlipid transport
A0009247biological_processglycolipid biosynthetic process
A0009274cellular_componentpeptidoglycan-based cell wall
A0016746molecular_functionacyltransferase activity
A0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
A0035375molecular_functionzymogen binding
A0046677biological_processresponse to antibiotic
A0050348molecular_functiontrehalose O-mycolyltransferase activity
A0071769biological_processmycolate cell wall layer assembly
B0004144molecular_functiondiacylglycerol O-acyltransferase activity
B0005576cellular_componentextracellular region
B0006869biological_processlipid transport
B0009247biological_processglycolipid biosynthetic process
B0009274cellular_componentpeptidoglycan-based cell wall
B0016746molecular_functionacyltransferase activity
B0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
B0035375molecular_functionzymogen binding
B0046677biological_processresponse to antibiotic
B0050348molecular_functiontrehalose O-mycolyltransferase activity
B0071769biological_processmycolate cell wall layer assembly
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue 6Y3 A 401
ChainResidue
ACYS209
AARG239
APHE252
APHE254
BTYR81

site_idAC2
Number of Residues10
Detailsbinding site for Di-peptide 6Y3 B 401 and CYS B 209
ChainResidue
BGLN236
BARG239
BPHE252
BASN253
BPHE254
BHOH556
ATYR81
BTYR208
BGLY210
BASN235

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Nucleophile => ECO:0000269|PubMed:10655617
ChainResidueDetails
ASER124
BSER124

site_idSWS_FT_FI2
Number of Residues4
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:10655617
ChainResidueDetails
AGLU228
AHIS260
BGLU228
BHIS260

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING:
ChainResidueDetails
ALEU40
BLEU40

site_idSWS_FT_FI4
Number of Residues10
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
ASER124
BHIS260
AASN152
ALEU230
ATHR237
AHIS260
BSER124
BASN152
BLEU230
BTHR237

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PDB entries from 2024-07-10

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