5KT2

Teranry complex of human DNA polymerase iota(26-445) inserting dCMPNPP opposite template G in the presence of Mg2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue 0KX A 501

Chain	Residue
A	ASP59
A	LYS102
A	ASP151
A	LYS239
A	MG502
A	MG503
A	HOH624
A	HOH632
A	HOH638
A	HOH645
P	DC873
A	LEU60
T	DG840
T	DG841
T	HOH904
A	ASP61
A	CYS62
A	PHE63
A	TYR64
A	THR90
A	TYR93
A	ARG96

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site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 502

Chain	Residue
A	ASP59
A	LEU60
A	ASP151
A	0KX501
A	MG503

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG A 503

Chain	Residue
A	ASP59
A	ASP151
A	GLU152
A	0KX501
A	MG502
P	DC873

---

site_id	AC4
Number of Residues	4
Details	binding site for residue MG A 504

Chain	Residue
A	LYS262
A	ILE264
A	ILE267
P	DC872

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00216

Chain	Residue	Details
A	GLU152

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:27555320, ECO:0007744|PDB:5KT5

Chain	Residue	Details
A	ASP59
A	LEU60
A	ASP151

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15254543, ECO:0007744|PDB:1T3N

Chain	Residue	Details
A	TYR64
A	ARG96

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