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5KRY

1-deoxy-D-xylulose 5-phosphate reductoisomerase from Vibrio vulnificus

Functional Information from GO Data
ChainGOidnamespacecontents
A0008299biological_processisoprenoid biosynthetic process
A0016491molecular_functionoxidoreductase activity
A0019288biological_processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
A0030145molecular_functionmanganese ion binding
A0030604molecular_function1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A0046872molecular_functionmetal ion binding
A0051484biological_processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
A0070402molecular_functionNADPH binding
B0008299biological_processisoprenoid biosynthetic process
B0016491molecular_functionoxidoreductase activity
B0019288biological_processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
B0030145molecular_functionmanganese ion binding
B0030604molecular_function1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B0046872molecular_functionmetal ion binding
B0051484biological_processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
B0070402molecular_functionNADPH binding
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue EDO A 501
ChainResidue
ALEU122
AASN124
ALYS125
APRO148
AASP150
AHIS153
AGLU234

site_idAC2
Number of Residues5
Detailsbinding site for residue EDO A 502
ChainResidue
AARG243
ACYS325
ATYR326
ATYR232
ASER242

site_idAC3
Number of Residues6
Detailsbinding site for residue EDO B 501
ChainResidue
BTYR232
BLYS236
BALA241
BSER242
BARG243
BCYS325

site_idAC4
Number of Residues8
Detailsbinding site for residue EDO B 502
ChainResidue
BLEU122
BASN124
BLYS125
BPRO148
BVAL149
BASP150
BHIS153
BGLU234

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues34
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00183","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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